After we could recently demonstrate a beneficial effect of environmental enrichment on AD-
like brain pathology in female TgCRND8 mice [Ambrée O, Leimer U, Herring A, Görtz N …

This study provides an examination of spatial learning and a behavioral assessment of
irritability and locomotion in TgCRND8 mice, an amyloid precursor protein transgenic model …

Although the impacts of environmental enrichment (EE) in several genetic models of
Alzheimer's disease (AD) have been documented, the focus has remained predominantly on …

Alzheimer's disease is a neurodegenerative disorder associated with age which represents
the most common cause of dementia. It is characterized by an accelerated memory loss …

Alzheimer's disease (AD) is accompanied by hippocampal neuronal loss and abnormal
neurogenesis, both of which probably contributing to AD-related cognitive deficits. Mounting …

Diversity and intensity of intellectual and physical activities seem to have an inverse
relationship with the extent of cognitive decline in Alzheimer's disease (AD). To study the …

Environmental enrichment (EE) is a process of brain stimulation by modifying the
surroundings, for example, by changing the sensory, social, or physical conditions. Rodents …

Transgenic mouse models of Alzheimer's disease (AD) have been recently advanced.
Tg2576 mice have been shown to develop progressive β-amyloid (Aβ) neuritic plaques and …

The most profound deficits observed in Alzheimer's disease (AD) are in domains of episodic
and working memory systems. Transgenic (Tg) mice expressing mutated human amyloid …

Environmental enrichment (EE) has been shown to improve neurological function and
cognitive performance in animal models of Alzheimer's disease (AD), Parkinson's disease …