The triple transgenic Alzheimer's disease (3xTg-AD) strain is a common mouse model used
for studying the pathology and mechanism of Alzheimer's disease (AD). The 3xTg-AD strain …

Which behavioral test is the most sensitive for detecting cognitive deficits in the 3xTg-AD at
6.5 months of age? The 3xTg-AD mouse model of Alzheimer's disease (AD) has three …

Alzheimer's disease (AD) is characterized by distinct behavioral and cognitive deficits that
differ from those observed in normal aging. Transgenic models of AD are a promising tool in …

The 3xTg-AD mouse model of Alzheimer's disease (AD) has both amyloid beta plaque and
tau tangle pathology. However, the results of behavioural testing with these mice have been …

Accumulation of amyloid‐β (Aβ) and fibrillary tangles, as well as neuroinflammation and
memory loss, are hallmarks of Alzheimer's disease (AD). After almost 15 years from their …

Alzheimer's disease is a progressive neurodegenerative disease that manifests as memory
loss, cognitive dysfunction, and dementia. Animal models of Alzheimer's disease have been …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common form of dementia. Approximately 50% of AD patients show anxiety and depressive …

The 5xFAD mouse model of Alzheimer's disease (AD) develops age-related neuropathology
and sensory, motor, and cognitive impairments. The purpose of this study was to examine …

The 5xFAD mouse model of Alzheimer's disease (AD) rapidly develops AD‐related neuro‐
behavioral pathology. Learning and memory impairments in 5xFAD mice, however, are not …

Background Several transgenic animal models genetically predisposed to develop
Alzheimer's disease (AD)-like pathology have been engineered to facilitate the study of …