Mechanisms underlying the protective effect of exercise training against the progression of
Alzheimer's disease (AD) are not fully understood. This study investigated the effects of …

Alzheimer's disease (AD) is a neurodegenerative pathology in which amyloid-β (Aβ) peptide
accumulates in different brain areas leading to deposition of plaques and a progressive …

In the present report, we extend previous findings in the 5XFAD mouse model with regard to
a characterization of behavioral deficits and neuropathological alterations. We demonstrate …

Alzheimer's disease is a neurodegenerative condition believed to be initiated by production
of amyloid-beta peptide, which leads to synaptic dysfunction and progressive memory loss …

Mouse models of Alzheimer's disease (AD) are often tested for learning and memory deficits
using visuo-spatial tasks such as the Morris water maze. Performance on these tasks is …

The neuropathological correlates of Alzheimer's disease (AD) include amyloid-β (Aβ)
plaques and neurofibrillary tangles. To study the interaction between Aβ and tau and their …

Despite the impact of pain in cognitive dysfunctions and affective disorders has been largely
studied, the research that examines pain dimensions in cognitive impairment or dementia is …

Alzheimer's disease (AD), the most common neurodegenerative and dementing disorder, is
characterized by extracellular amyloid deposition, intracellular neurofibrillary tangle …

Mouse models of Alzheimer's disease (AD) show both cognitive and neuromotor
impairments. We measured motor ability and motor learning of male and female triple …

Depression is among the most frequent psychiatric comorbid conditions in Alzheimer
disease (AD). However, pharmacotherapy for depressive disorders in AD is still a big …