[HTML][HTML] HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

[HTML][HTML] Antiretroviral therapy in HTLV-1 infection: an updated overview

F Marino-Merlo, E Balestrieri, C Matteucci, A Mastino… - Pathogens, 2020 - mdpi.com
The human T cell leukemic/lymphotropic virus type 1 (HTLV-1), discovered several years
ago, is the causative agent for a rapid progressive haematological malignancy, adult T cell …

[HTML][HTML] Comparative virology of HTLV-1 and HTLV-2

MP Martinez, J Al-Saleem, PL Green - Retrovirology, 2019 - Springer
Human T cell leukemia virus type 1 (HTLV-1) was the first discovered human retrovirus and
the etiologic agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropical …

Human T cell leukemia virus type 1: persistence and pathogenesis

CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …

[HTML][HTML] 40 years of the human T-cell leukemia virus: past, present, and future

Y Tagaya, M Matsuoka, R Gallo - F1000Research, 2019 - ncbi.nlm.nih.gov
It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

Reducing the global burden of HTLV-1 infection: an agenda for research and action

L Willems, H Hasegawa, R Accolla, C Bangham… - Antiviral research, 2017 - Elsevier
Even though an estimated 10–20 million people worldwide are infected with the oncogenic
retrovirus, human T-lymphotropic virus type 1 (HTLV-1), its epidemiology is poorly …

[HTML][HTML] Time to eradicate HTLV-1: an open letter to WHO

F Martin, Y Tagaya, R Gallo - The Lancet, 2018 - thelancet.com
Human T-cell leukaemia virus 1 (HTLV-1) is the most potent carcinogenic oncovirus and
potentially the most oncogenic risk factor including chem ical carcinogens. 1 A unique and …

[HTML][HTML] HTLV-1 and co-infections

C Rosadas, GP Taylor - Frontiers in Medicine, 2022 - frontiersin.org
HTLV-1 is a retrovirus that causes lifelong T-cell infection in humans, impacting the host
immune response. This virus causes a range of clinical manifestations, from inflammatory …

The discovery of HTLV-1, the first pathogenic human retrovirus

JM Coffin - Proceedings of the National Academy of …, 2015 - National Acad Sciences
After the discovery of retroviral reverse transcriptase in 1970, there was a flurry of activity,
sparked by the “War on Cancer,” to identify human cancer retroviruses. After many false …

[HTML][HTML] HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP

P Miyazato, M Matsuo, BJY Tan, M Tokunaga… - Retrovirology, 2019 - Springer
Background Human T cell leukaemia virus type 1 (HTLV-1) is a retrovirus associated with
human diseases such as adult T-cell leukaemia/lymphoma and HTLV-1 associated …