Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

The term human T-cell leukemia virus (HTL V) denotes a unique family of T-cell
lymphotropic, pathogenic retroviruses. The discovery ofHTLV-I, a virus belonging to this …

Co-infection with HTLV-1 reaches 20% among patients infected by HIV-1 in Bahia, Brazil. To
evaluate its impact on survival, we conducted a retrospective, case–control study involving …

The deltaretroviruses human T cell lymphotropic virus type 1 (HTLV-1) and human T cell
lymphotropic virus type 2 (HTLV-2) have long been believed to differ from retroviruses in …

Because HTLV-I, HTLV-2, and HIV share identical modes of transmission, simultaneous or
subsequent infections with these retroviruses are to be expected. The population of Santos …

The human retrovirus human T-lymphotropic virus type 1 (HTLV-1) is associated with two
distinct types of disease: the malignancy known as adult T-cell leukemia and a range of …

Highlights•Molecular mechanisms of HTLV-1 oncogenesis.•Innate and acquired immune
response to HTLV-1.•Clonality of HTLV-1 in vivo.•We bring together the host and viral factors …

Abstract Background Human T-lymphotropic Virus Type I (HTLV-1) is a retrovirus that
persistently infects 5–10 million individuals worldwide and causes disabling or fatal …

Among viruses the human retroviruses may be of special interest to immunologists, because
they target cells of the immune system, particularly mature CD4+ T cells, impair their function …

Despite being discovered in animals in the early 20th century, the scientific interest in
retroviruses was boosted with the discovery of human retroviruses (human T …