Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen in humans. Diseases caused by cryptococcal infections account for up to 200,000 …

The fungal pathogen Cryptococcus neoformans relies on post-transcriptional mechanisms of
gene regulation to adapt to stressors it encounters in the human host, such as oxidative …

Cryptococcus neoformans is one of the few environmental fungi that can survive within a
mammalian host and cause disease. Although many of the factors responsible for …

Cryptococcus neoformans kills 200,000 people worldwide each year. After inhalation, this
environmental yeast proliferates either extracellularly or within host macrophages. Under …

Cryptococcus neoformans is one of the few environmental fungi that can adapt to a
mammalian host and cause disease. As free a living organism, C. neoformans is challenged …

Upon Cryptococcus neoformans infection of the host lung, the fungus enters a nutrient poor
environment and must adapt to a variety of host-specific stress conditions (temperature …

Cryptococcus neoformans is the etiological agent for the disease, cryptococcal meningitis,
affecting approximately 250,000 individuals, with an estimated 180,000 attributable deaths …

In response to the host environment, the human pathogen Cryptococcus neoformans must
rapidly reprogram its translatome from one which promotes growth to one which is …

Proper regulation of metabolism is essential to maximizing fitness of organisms in their
chosen environmental niche. Nitrogen metabolite repression is an example of a regulatory …

Cryptococcus neoformans is an environmental yeast and an opportunistic human pathogen.
The ability to cause disease depends on the ability to adapt to the human host. Previous …