The role of genetic risk factors for ischemic stroke seems to be in particular significance in
pediatric patients. Numerous polymorphic variants of genes encoding proteins, that is …

The plasminogen activator inhibitor-1 (PAI-1) is a candidate gene for stroke based on PAI-
1's crucial role in fibrinolytic system. However, association studies have yielded conflicting …

Pediatric ischemic stroke, though relatively rare, remains an important medical problem
since 20− 40% of patients have recurrent strokes and 50− 85% of them suffer from long-term …

Mechanisms of ischemic stroke in young adults are poorly understood. The aim of the study
was to investigate and compare the frequency of common variations in prothrombotic genes …

Background Prolonged euglobulin clot lysis time (ECLT) and increased level of
plasminogen activator inhibitor-1 (PAI-1) were reported to be risk factors of arterial ischemic …

To investigate whether the 4G/5G polymorphism of plasminogen activator inhibitor type 1
(PAI-1) and the− 7351 C/T polymorphism of tissue-type plasminogen activator (t-PA) are …

The plasminogen activator inhibitor-1 (PAI-1) gene has been found to be associated with the
pathogenesis and progression of vascular diseases including stroke. A 4G/5G, PAI-1 gene …

Background Previous data have shown that the 20210G> A polymorphism of the Factor II
gene is related to an increased prothrombin level, which may in turn lead to a procoagulant …

A common polymorphism of the FXIIIA gene, which is characterized by a Val→ Leu
exchange at amino acid position 34 (FXIII Val34Leu), was studied in this case-control study …

The incidence of arterial ischemic stroke (AIS) in childhood (about 2–13 per 100,000
children a year) is much lower than the incidence in the adult population. Still, adverse …