In Situ Imaging of Virus-Infected Cells by Cryo-Electron Tomography: An Overview
S Vijayakrishnan - Virus Infected Cells, 2023 - Springer
Cryo-electron tomography (cryo-ET) has emerged as a powerful tool in structural biology to
study viruses and is undergoing a resolution revolution. Enveloped viruses comprise several …
study viruses and is undergoing a resolution revolution. Enveloped viruses comprise several …
Cryo-electron tomography: the resolution revolution and a surge of in situ virological discoveries
Y Hong, Y Song, Z Zhang, S Li - Annual Review of Biophysics, 2023 - annualreviews.org
The recent proliferation of cryo-electron tomography (cryo-ET) techniques has led to the cryo-
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …
Cryo-electron tomography to study viral infection
M Graham, P Zhang - Biochemical Society Transactions, 2023 - portlandpress.com
Developments in cryo-electron microscopy (cryo-EM) have been interwoven with the study
of viruses ever since its first applications to biological systems. Following the success of …
of viruses ever since its first applications to biological systems. Following the success of …
Cryo-Electron Microscopy and Cryo-Electron Tomography of Viruses
When viruses are viewed as dynamic containers of an infectious genome, their structural,
physical, and biochemical analyses become necessary to understand the molecular …
physical, and biochemical analyses become necessary to understand the molecular …
Cryo-electron tomography of enveloped viruses
S Li - Trends in Biochemical Sciences, 2022 - cell.com
Viruses are macromolecular machineries that hijack cellular metabolism for replication.
Enveloped viruses comprise a large variety of RNA and DNA viruses, many of which are …
Enveloped viruses comprise a large variety of RNA and DNA viruses, many of which are …
Cellular electron cryo-tomography to study virus-host interactions
ERJ Quemin, EA Machala, B Vollmer… - Annual review of …, 2020 - annualreviews.org
Viruses are obligatory intracellular parasites that reprogram host cells upon infection to
produce viral progeny. Here, we review recent structural insights into virus-host interactions …
produce viral progeny. Here, we review recent structural insights into virus-host interactions …
Structure of complex viruses and virus-infected cells by electron cryo tomography
K Grünewald, M Cyrklaff - Current opinion in microbiology, 2006 - Elsevier
In microbiology, and in particular in virus research, electron microscopy (EM) is an important
tool, offering a broad approach for investigating viral structure throughout their intracellular …
tool, offering a broad approach for investigating viral structure throughout their intracellular …
Analysis of Viruses in the Cellular Context by Electron Tomography
P Zhang, L Mendonça - Encyclopedia of Virology: Volume 1-5 …, 2020 - experts.umn.edu
Electron microscopy is a powerful tool to study viral infection in the cellular context. A vast
majority of our ultrastructural understanding of cellular infection has been acquired through …
majority of our ultrastructural understanding of cellular infection has been acquired through …
Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography
The past few decades have seen tremendous advances in single-particle electron cryo-
microscopy (cryo-EM). The field has matured to the point that near-atomic resolution density …
microscopy (cryo-EM). The field has matured to the point that near-atomic resolution density …
Dissecting virus infectious cycles by cryo-electron microscopy
KK Lee, L Gui - PLOS pathogens, 2016 - journals.plos.org
In response to events such as receptor binding and endocytic triggers, viruses undergo
largescale, dynamic conformational changes necessary for cell entry and genome delivery …
largescale, dynamic conformational changes necessary for cell entry and genome delivery …
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