The prognostic value of ABC transporters in Ewing sarcoma is still poorly explored and
controversial. We described for the first time the impact of various ABCs on Ewing sarcoma …

Abstract Introduction: Ewing Sarcoma (EWS), the second most common bone tumor
occurring in children and young adults, is a clinically very aggressive tumor with high …

Purpose The relevance of the subfamily A members of ATP-binding cassette (ABCA)
transporters as biomarkers of risk and response is emerging in different tumors, but their …

Overexpression of ATP-binding cassette (ABC) transporters is a cause of drug resistance in
a plethora of tumors. More recent evidence indicates additional contribution of these …

The ATP-binding cassette (ABC) transporter superfamily consists of several proteins with a
wide repertoire of functions. Under physiological conditions, ABC transporters are involved …

Simple Summary Ewing sarcoma is a cancer arising most frequently in teenagers and young
adults. For many patients, outcomes are the same today as they were 30 years ago …

ATP-binding cassette transporters (ABC transporters) regulate traffic of multiple compounds,
including chemotherapeutic agents, through biological membranes. They are expressed by …

The goal of this Special Issue on “ABC Transporters in Human Diseases”, for which I was
invited as a Guest Editor, was to provide an overview of the state-of-the-art research …

Neuroblastoma is the most common cancer of infancy and accounts for 15% of all pediatric
oncology deaths. Survival rates of high-risk neuroblastoma remain less than 50%, with …

ATP-binding-cassette subfamily E member 1 (ABCE1) has been identified as an essential
component of RNA translation and cell proliferation. However, studies on its role in pan …