Dynamics and implications of circulating anti-angiogenic VEGF-A165b isoform in patients with ST-elevation myocardial infarction

L Hueso, C Rios-Navarro, A Ruiz-Sauri, FJ Chorro… - Scientific reports, 2017 - nature.com
Angiogenesis is crucial to restore microvascular perfusion in the jeopardized myocardium in
the weeks following reperfused ST-segment elevation myocardial infarction (STEMI).(VEGF) …

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction

C Ríos-Navarro, L Hueso, A Díaz… - Revista Española de …, 2021 - Elsevier
Introduction and objectives Angiogenesis helps to reestablish microcirculation after
myocardial infarction (MI). In this study, we aimed to further understand the role of the …

[HTML][HTML] Association between the ratio of anti-angiogenic isoform of VEGF-A to total VEGF-A and adverse clinical outcomes in patients after acute myocardial infarction

K Harada, R Kikuchi, H Ishii, Y Shibata, S Suzuki… - IJC heart & …, 2018 - Elsevier
Background Vascular endothelial growth factor-A (VEGF-A) promotes neovascularization
and is attracting considerable attention as a remarkable risk factor in patients after acute …

Vascular endothelial growth factor (VEGF)-A: role on cardiac angiogenesis following myocardial infarction

T Zhao, W Zhao, Y Chen, RA Ahokas, Y Sun - Microvascular research, 2010 - Elsevier
The current study is to determine the regulatory role of VEGF-A in cardiac angiogenesis
following myocardial infarction (MI). Cardiac angiogenic response and temporal/spatial …

VEGF-A plasma levels are associated with microvascular obstruction in patients with ST-segment elevation myocardial infarction

R Garcia, C Bouleti, M Sirol, D Logeart… - International Journal of …, 2019 - Elsevier
Background Microvascular obstruction (MVO) is associated with poor outcome after ST-
segment elevation myocardial infarction (STEMI). Vascular endothelial growth factor-A …

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium

X Li, M Tjwa, I Van Hove, B Enholm… - … , and vascular biology, 2008 - Am Heart Assoc
Objective—The endogenous role of the VEGF family member vascular endothelial growth
factor-B (VEGF-B) in pathological angiogenesis remains unclear. Methods and Results—We …

VEGF-B taken to our hearts: specific effect of VEGF-B in myocardial ischemia

L Claesson-Welsh - Arteriosclerosis, thrombosis, and vascular …, 2008 - Am Heart Assoc
Vascular endothelial growth factor-B (VEGF-B, see Olofsson et al1) is one of 5 mammalian
VEGF family members, the others being VEGF-A, VEGF-C, VEGF-D, and placental growth …

Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1–and neuropilin …

JE Lähteenvuo, MT Lähteenvuo, A Kivelä… - Circulation, 2009 - Am Heart Assoc
Background—New revascularization therapies are urgently needed for patients with severe
coronary heart disease who lack conventional treatment options. Methods and Results—We …

Macrophages overexpressing VEGF target to infarcted myocardium and improve neovascularization and cardiac function

D Yan, X Wang, D Li, W Liu, M Li, Z Qu… - International journal of …, 2013 - Elsevier
BACKGROUND: Clinical trials of vascular endothelial growth factor (VEGF) gene therapy
have proven that VEGF has beneficial effects on the ischemic heart disease; however, the …

Synergistically therapeutic effects of VEGF165 and angiopoietin-1 on ischemic rat myocardium

X Liu, Y Chen, F Zhang, L Chen, T Ha… - Scandinavian …, 2007 - Taylor & Francis
Purpose. The aim of this study was to determine whether the combination of 2 angiogenic
growth factor, vascular endothelial growth factor 165 (VEGF165) and angiopoietin-1 (Ang1) …