Wearable inertial sensors are highly sensitive in the detection of gait disturbances and fatigue at early stages of multiple sclerosis

R Müller, D Hamacher, S Hansen, P Oschmann… - BMC neurology, 2021 - Springer
Background The aim of the current study was to examine multiple gait parameters obtained
by wearable inertial sensors and their sensitivity to clinical status in early multiple sclerosis …

Free-living and laboratory gait characteristics in patients with multiple sclerosis

FA Storm, KPS Nair, AJ Clarke, JM Van der Meulen… - PloS one, 2018 - journals.plos.org
Background Wearable sensors offer the potential to bring new knowledge to inform
interventions in patients affected by multiple sclerosis (MS) by thoroughly quantifying gait …

Clinical assessment of gait in individuals with multiple sclerosis using wearable inertial sensors: Comparison with patient-based measure

M Pau, S Caggiari, A Mura, F Corona, B Leban… - Multiple sclerosis and …, 2016 - Elsevier
Background This study aims to verify the feasibility of use of wearable accelerometers in an
ambulatory environment to assess spatiotemporal parameters of gait in people with Multiple …

Wearable sensors can reliably quantify gait alterations associated with disability in people with progressive multiple sclerosis in a clinical setting

L Angelini, W Hodgkinson, C Smith, JM Dodd… - Journal of …, 2020 - Springer
Gait disability in people with progressive multiple sclerosis (MS) is difficult to quantify using
existing clinical tools. This study aims to identify reliable and objective gait-based …

Stability of sensor-based gait parameters reassessed after a period of one year in people with multiple sclerosis

R Müller, D Hamacher, PM Keune, P Oschmann - BMC neurology, 2023 - Springer
Background Currently, there are several studies showing that wearable inertial sensors are
highly sensitive in the detection of gait disturbances in people with multiple sclerosis …

Wearable inertial sensors provide reliable biomarkers of disease severity in multiple sclerosis: A systematic review and meta-analysis

A Vienne-Jumeau, F Quijoux, PP Vidal… - Annals of physical and …, 2020 - Elsevier
Background Gait impairment is a hallmark of multiple sclerosis (MS). InertiaLocoGraphy, the
quantification of gait with inertial measurement units (IMUs), has been found useful to detect …

Disability and fatigue can be objectively measured in multiple sclerosis

C Motta, E Palermo, V Studer, M Germanotta… - PLoS …, 2016 - journals.plos.org
Background The available clinical outcome measures of disability in multiple sclerosis are
not adequately responsive or sensitive. Objective To investigate the feasibility of inertial …

Short inertial sensor-based gait tests reflect perceived state fatigue in multiple sclerosis

AA Ibrahim, F Flachenecker, H Gaßner… - Multiple Sclerosis and …, 2022 - Elsevier
Background Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the
central nervous system, affecting more than 2.3 million people worldwide. Fatigue is among …

Value of gait analysis for measuring disease severity using inertial sensors in patients with multiple sclerosis: protocol for a systematic review and meta-analysis

A Vienne-Jumeau, F Quijoux, PP Vidal, D Ricard - Systematic Reviews, 2019 - Springer
Background Gait impairment is a hallmark of multiple sclerosis (MS) which significantly
endangers the quality of life of the individual. Inertial measurement units (IMUs) are small …

Inertial sensor-based gait parameters reflect patient-reported fatigue in multiple sclerosis

AA Ibrahim, A Küderle, H Gaßner, J Klucken… - … of neuroengineering and …, 2020 - Springer
Background Multiple sclerosis (MS) is a disabling disease affecting the central nervous
system and consequently the whole body's functional systems resulting in different gait …