Drug addiction is likely to affect all of our lives, with any luck not through our own actions but
probably because of one or more of our family and friends. Now firmly entrenched as a brain …

Repeated drug use can change dopamine (DA) function in ways that promote the
development and persistence of addiction, but in what direction? By one view, drug use …

We consider conditioned taste aversion to involve a learned reduction in the palatability of a
taste (and hence in amount consumed) based on the association that develops when a taste …

Drug addiction can be defined by a compulsion to seek and take drug, loss of control in
limiting intake, and the emergence of a negative emotional state when access to the drug is …

Drug addiction is a syndrome of dysregulated motivation, evidenced by intense drug craving
and compulsive drug-seeking behavior. In the search for common neurobiological …

Most psychoactive drugs are capable of inducing gustatory aversions. This review
addresses itself to several major issues deriving from this fact. Among the questions …

The development of addiction and vulnerability to relapse following withdrawal is proposed
to be the result of neuroadaptive processes within the central nervous system that oppose …

Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses
through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation …

Not the mere procurement and use of drugs, but the fact that patterns of seeking and taking
become compulsive after prolonged drug use is a defining characteristic of drug addiction …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …