Cancer-causing mutations disrupt coordinated, precise programs of gene expression that
govern cell growth and differentiation. Microarray-based gene-expression profiling (GEP) is …

Multiple myeloma (MM) remains incurable despite high-dose chemotherapy with stem cell
support. There is need, therefore, for continuous efforts directed toward the development of …

The past decade has seen significant advances in our understanding and treatment of
multiple myeloma (MM) and its precursor diseases. These advances include gains in …

Multiple myeloma remains largely incurable despite conventional and high-dose therapies,
and so novel biologically based treatment approaches are urgently required. Recent studies …

Despite significant advances in the treatment of multiple myeloma which had led to
unprecedented rates of response and survival, patients still relapse, and cure remains …

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by aberrant expansion of
plasma cells within bone marrow and extramedullary sites. It is one of the most common …

Multiple myeloma (MM) remains largely incurable despite conventional and high‐dose
therapies, and novel biologically based treatment approaches are urgently required. Recent …

Multiple myeloma (MM) is a clinically and genetically heterogeneous plasma cell (PC)
malignancy. Whole-exome sequencing has identified therapeutically targetable mutations …

Simple Summary This article provides a comprehensive review of new and emerging
treatment strategies against multiple myeloma that employ precision medicines and/or drugs …

Despite the advent of many therapeutic agents, such as bortezomib and lenalidomide that
have significantly improved the overall survival, multiple myeloma remains an incurable …