Objectives This preclinical study was devised to investigate potential cellular toxicity in
human neurons induced by gadolinium-based contrast agents (GBCAs) used for contrast …

Purpose To determine if repeated intravenous exposures to gadolinium-based contrast
agents (GBCAs) are associated with neuronal tissue deposition. Materials and Methods In …

Gadolinium (Gd), a rare-earth lanthanides metal, is widely utilized for various industrial and
medical purposes, particularly in brain magnetic resonance imaging. However, its potential …

Background Concerns over the neurotoxic potential of retained gadolinium in brain tissues
after intravenous gadolinium-based contrast agent (GBCA) administration have led to …

Purpose Gadolinium is a rare-earth lanthanide metal that is known to have a direct
neurotoxic effect. The scope of the present review is to summarize the current preclinical and …

Background and purpose Gadolinium based contrast agents (GBCAs) are widely used in
magnetic resonance imaging, but recently, high signal intensity in the cerebellum structures …

Purpose To determine whether gadolinium deposits in neural tissues of patients with
intracranial abnormalities following intravenous gadolinium-based contrast agent (GBCA) …

Purpose To investigate the long-term course of MRI signal intensity (SI) changes and the
presence of gadolinium in the rat brain during a 1-year period after multiple administrations …

Objectives The aim of this study was to evaluate Gd retention in the deep cerebellar nuclei
(DCN) of linear gadolinium-based contrast agents (GBCAs) compared with a macrocyclic …

The established class of intravenous contrast media for magnetic resonance imaging is the
gadolinium chelates, more generally referred to as the gadolinium-based contrast agents …