Alzheimer's disease (AD) is the most common cause of dementia worldwide, but the
molecular and cellular mechanisms underlying cognitive impairment remain poorly …

Neurodegenerative diseases are known to affect neural plasticity and memory. While the
cellular and molecular basis of many neurodegenerative diseases is increasingly clear, how …

The hippocampus is vulnerable to deterioration in Alzheimer's disease (AD). It is, however, a
heterogeneous structure, which may contribute to the differential volumetric changes along …

Abstract Changes in high-affinity nicotinic acetylcholine receptors are intricately connected
to neuropathology in Alzheimer's Disease (AD). Protective and cognitive-enhancing roles for …

Alzheimer's disease (AD) is an age-dependent incurable neurodegenerative disorder
accompanied by neuroinflammation, amyloid accumulation and memory impairment. It …

Functional activity alterations are one of the earliest hallmarks of Alzheimer's disease (AD),
already detected prior to beta-amyloid plaque and tau-tangle accumulation. To reveal the …

Alzheimer's disease (AD) is a chronic, nonlinearly progressive neurodegenerative disease
that affects multiple domains of behaviour and is the most common form of dementia …

Alzheimer's disease is the most prevalent neurodegenerative disease and is characterized
by progressive memory loss and cognitive decline, affecting behavior, speech, and motor …

Early Alzheimer's disease (AD) is marked by cholinergic hypofunction, neuronal marker loss,
and decreased nicotinic acetylcholine receptor (nAChR) density from the cortex and …

Cholinergic system dysfunction has been considered as a critical feature of
neurodegenerative progression in Alzheimer's disease (AD). The α7 nicotinic acetylcholine …