[HTML][HTML] Potential and applications of nanocarriers for efficient delivery of biopharmaceuticals

A Zeb, I Rana, HI Choi, CH Lee, SW Baek, CW Lim… - Pharmaceutics, 2020 - mdpi.com
During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …

Recent advances in nanocarrier-based mucosal delivery of biomolecules

O Kammona, C Kiparissides - Journal of controlled release, 2012 - Elsevier
This review highlights the recent developments in the area of nanocarrier-based mucosal
delivery of therapeutic biomolecules and antigens. Macromolecular drugs have the unique …

Nanocarriers for oral delivery of biologics: small carriers for big payloads

Y Cao, P Rewatkar, R Wang, SZ Hasnain… - Trends in …, 2021 - cell.com
Macromolecular therapeutics of biological origin, also known as biologics, have become
one of the fastest-growing classes of drugs for management of a range of chronic and acute …

The fate of nanocarriers as nanomedicines in vivo: important considerations and biological barriers to overcome

M Moros, SG Mitchell, V Grazu - Current Medicinal Chemistry, 2013 - ingentaconnect.com
Many pharmaceuticals on the market suffer from two significant limitations to their activity:
lack of specificity toward the pathological site and poor aqueous solubility. Both factors …

New aspects of nanopharmaceutical delivery systems

PD Marcato, N Durán - Journal of nanoscience and …, 2008 - ingentaconnect.com
Nanobiotechnology, involving biological systems manufactured at the molecular level, is a
multidisciplinary field that has fostered the development of nanoscaled pharmaceutical …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Drug-loaded nanocarriers: passive targeting and crossing of biological barriers

JM Rabanel, V Aoun, I Elkin… - Current medicinal …, 2012 - ingentaconnect.com
Poor bioavailability and poor pharmacokinetic characteristics are some of the leading
causes of drug development failure. Therefore, poorly-soluble drugs, fragile proteins or …

Nanocarriers based novel and effective drug delivery system

S Khizar, N Alrushaid, FA Khan, N Zine… - International Journal of …, 2023 - Elsevier
Nanotechnology has ultimately come into the domain of drug delivery. Nanosystems for
delivery of drugs are promptly emerging science utilizing different nanoparticles as carriers …

Nanocarriers for drug delivery: mini review

V Girdhar, S Patil, S Banerjee… - … : Recent Patents on …, 2018 - ingentaconnect.com
Background: Nanocarriers have been a part of drug delivery for some decades now. Due to
the enormous advantages offered by them, they are replacing the conventionally available …

Nanocarrier-based systems for targeted and site specific therapeutic delivery

J Majumder, O Taratula, T Minko - Advanced drug delivery reviews, 2019 - Elsevier
Systemic drug delivery methods such as oral or parenteral administration of free drugs
possess relatively low treatment efficiency and marked adverse side effects. The use of …