Nanophthalmos is a rare, potentially devastating eye condition characterized by small eyes
with relatively normal anatomy, a high hyperopic refractive error, and frequent association …

Purpose Nanophthalmos is a rare subtype of microphthalmia associated with high
hyperopia and an increased risk of angle-closure glaucoma. We investigated the genetic …

Purpose Nanophthalmos is a rare genetic ocular disorder in which the eyes of affected
individuals are abnormally small. Patients suffer from severe hyperopia as a result of their …

Purpose: Nanophthalmos is a rare genetic disorder commonly characterized by a short axial
length (AL) and severe hyperopia. Mutations that have been identified through Mendelian …

This study aimed to genetically and clinically characterize a unique cohort of 25 individuals
from 21 unrelated families with autosomal recessive nanophthalmos (NNO) and posterior …

Nanophthalmos is a rare condition defined by a small, structurally normal eye with resultant
high hyperopia. While six genes have been implicated in this hereditary condition (MFRP …

Purpose To (i) describe a series of patients with isolated or syndromic nanophthalmos with
the underlying genetic causes, including novel pathogenic variants and their functional …

The precise control of eye size is essential for normal vision. TMEM98 is a highly conserved
and widely expressed gene which appears to be involved in eye size regulation. Mutations …

Purpose Autosomal dominant nanophthalmos is an inherited eye disorder characterized by
a structurally normal but smaller eye. Patients with nanophthalmos have high hyperopia (far …

Importance Nanophthalmos is a congenital disorder characterized by small eyes, with the
main complications being severe hyperopia and angle-closure glaucoma. Objective To …