Biotin and chromium histidinate improve glucose metabolism and proteins expression levels of IRS-1, PPAR-γ, and NF-κB in exercise-trained rats

M Turgut, V Cinar, R Pala, M Tuzcu, C Orhan… - Journal of the …, 2018 - Springer
Abstract Background Chromium histidinate (CrHis) and biotin are micronutrients commonly
used to improve health by athletes and control glycaemia by patients with diabetes. This …

Effect of supplementing chromium histidinate and picolinate complexes along with biotin on insulin sensitivity and related metabolic indices in rats fed a high‐fat diet

C Orhan, O Kucuk, M Tuzcu, N Sahin… - Food science & …, 2019 - Wiley Online Library
Scope To investigate the effects of chromium histidinate (CrHis) and chromium picolinate
(CrPic) complex along with biotin to a high‐fat diet (HFD) fed to rats on the insulin sensitivity …

Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocin

K Sahin, M Tuzcu, C Orhan, N Sahin… - British Journal of …, 2013 - cambridge.org
The objective of the present study was to evaluate anti-diabetic effects of chromium
picolinate (CrPic) and biotin supplementations in type 2 diabetic rats. The type 2 diabetic rat …

Impact of chromium histidinate on high fat diet induced obesity in rats

M Tuzcu, N Sahin, C Orhan, CA Agca, F Akdemir… - Nutrition & …, 2011 - Springer
Abstract Background Chromium (Cr) is an essential trace element that has garnered interest
for use as a weight loss aid, but its molecular mechanism in obesity is not clear. In this study …

Effects of supplementing different chromium histidinate complexes on glucose and lipid metabolism and related protein expressions in rats fed a high-fat diet

K Sahin, O Kucuk, C Orhan, F Erten, N Sahin… - Journal of Trace …, 2021 - Elsevier
Background The objective of this study was to investigate the effects of different chromium
histidinate (CrHis) complexes added to the diet of rats fed a high-fat diet (HFD) on body …

The effects of chromium picolinate on glucose and lipid metabolism in running rats

R Pala, MA Sari, F Erten, B Er, M Tuzcu, C Orhan… - Journal of Trace …, 2020 - Elsevier
Abstract Background Chromium picolinate (CrPic) is commonly used to reduce muscle
fatigue after exercise. We aimed to elucidate the effects of CrPic on glucose and lipid …

Pharmacological concentrations of biotin reduce serum triglycerides and the expression of lipogenic genes

E Larrieta, F Velasco, P Vital, T López-Aceves… - European journal of …, 2010 - Elsevier
Besides its role as a carboxylase prosthetic group, biotin regulates gene expression and has
a wide repertoire of effects on systemic processes. Several studies have shown that …

Protective effect of supplementation with biotin against high-fructose-induced metabolic syndrome in rats

A Aguilera-Mendez, MG Hernández-Equihua… - Nutrition research, 2018 - Elsevier
Several reports have demonstrated that pharmacological concentrations of biotin reduce
hyperglycemia, hypertriglyceridemia, and hypertension. We hypothesized that biotin could …

Chromium dinicocysteinate supplementation can lower blood glucose, CRP, MCP‐1, ICAM‐1, creatinine, apparently mediated by elevated blood vitamin C and …

SK Jain, JL Croad, T Velusamy… - Molecular nutrition & …, 2010 - Wiley Online Library
Chromium and cysteine supplementation can improve glucose metabolism in animal
studies. This study examined the hypothesis that a cysteinate complex of chromium is …

Exercise affects blood glucose levels and tissue chromium distribution in high-fat diet-fed C57BL6 mice

GR Chang, PH Hou, WK Chen, CT Lin, HP Tsai… - Molecules, 2020 - mdpi.com
Obesity is commonly associated with hyperglycemia and type 2 diabetes and negatively
affects chromium accumulation in tissues. Exercise prevents and controls obesity and type 2 …