Recent advances in neuroepigenetics have revealed its essential role in governing body
function and disease. Epigenetics regulates an array of mechanisms that are susceptible to …

The beginnings of late onset Alzheimer's disease (LOAD) are still unknown; however, the
progressive and latent nature of neurodegeneration suggests that the triggering event …

Lead exposure has primarily been a concern during development in young children and
little attention has been paid to exposure outcomes as these children age, or even to …

Alzheimer's disease (AD) and Parkinson's disease (PD) are two common
neurodegenerative diseases that result in the progressive damage or death of neurons …

Developmental lead (Pb) exposure results in persistent cognitive/behavioral impairments as
well as an elevated risk for developing a variety of diseases in later life. Environmental …

The epigenetic machinery plays a pivotal role in the control of many of the body's key
cellular functions. It modulates an array of pliable mechanisms that are readily and durably …

In this study, we assessed global gene expression patterns in adolescent mice exposed to
lead (Pb) as infants and their aged siblings to identify reprogrammed genes. Global …

Lead (Pb) exposure has been a major public health concern for a long time now due to its
permanent adverse effects on the human body. The process of lead toxicity has still not been …

Lead (Pb) exposure is associated with a wide range of neurological deficits. Environmental
exposures may impact epigenetic changes, such as DNA methylation, and can affect …

Abstract Changes in DNA methylation and subsequent changes in gene expression
regulation are the hallmarks of age-and tissue-dependent epigenetic drift and plasticity …