A 35-year-old Caucasian male presented with chest pain and nausea in the emergency
room. The initial ECG displayed sinus-rhythm with ST elevation in I, aVL, V1–5, ST …

Noninvasive imaging strategies will be critical for defining the temporal characteristics of
angiogenesis and assessing efficacy of angiogenic therapies. The αvβ3 integrin is …

Aims The purpose of this study was to determine the feasibility of a new positron emission
tomography (PET) imaging approach using an 18F-labelled αvβ3 integrin antagonist (18F …

18F-galacto-RGD (18F-RGD) is a PET tracer binding to αvβ3 integrin receptors that are
upregulated after myocardial infarction (MI) as part of the healing process. We studied …

Background Radiolabeled RGD peptides detect α v β 3 integrin expression associated with
angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied …

Purpose Increased angiogenesis after myocardial infarction is considered an important
favorable prognostic parameter. The αvβ3 integrin is a key mediator of cell-cell and cell …

Background—Noninvasive imaging strategies play a critical role in assessment of the
efficacy of angiogenesis therapies. The αvβ3 integrin is activated in angiogenic vessels and …

The αvβ3-integrin is expressed in angiogenic vessels in response to hypoxia and represents
a potential novel target for imaging myocardial angiogenesis. This study evaluated the …

Background Inflammation and angiogenesis play an important role in atherosclerotic plaque
rupture. Therefore, molecular imaging of these processes could be used for determination of …

Objective Maladaptive repair contributes towards the development of heart failure following
myocardial infarction (MI). The αvβ3 integrin receptor is a key mediator and determinant of …