[HTML][HTML] Connectivity-based parcellation reveals distinct cortico-striatal connectivity fingerprints in Autism Spectrum Disorder

JH Balsters, D Mantini, N Wenderoth - Neuroimage, 2018 - Elsevier
Abstract Autism Spectrum Disorder (ASD) has been associated with abnormal synaptic
development causing a breakdown in functional connectivity. However, when measured at …

Genes, synapses and autism spectrum disorders

T Bourgeron - Synaptic Plasticity and the Mechanism of Alzheimer's …, 2008 - Springer
Autism spectrum disorders (ASD) can be the consequences of genetic anomalies affecting
distinct physiological processes such as chromatin remodeling (MECP2), synaptic gene …

[HTML][HTML] Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

MC Postema, D Van Rooij, E Anagnostou… - Nature …, 2019 - nature.com
Altered structural brain asymmetry in autism spectrum disorder (ASD) has been reported.
However, findings have been inconsistent, likely due to limited sample sizes. Here we …

Hyperexcitability and hyperplasticity disrupt cerebellar signal transfer in the IB2 KO mouse model of autism

T Soda, L Mapelli, F Locatelli, L Botta… - Journal of …, 2019 - Soc Neuroscience
Autism spectrum disorders (ASDs) are pervasive neurodevelopmental conditions that often
involve mutations affecting synaptic mechanisms. Recently, the involvement of cerebellum in …

Developmental pattern of the cortical topology in high‐functioning individuals with autism spectrum disorder

W Zheng, Z Zhao, Z Zhang, T Liu, Y Zhang… - Human Brain …, 2021 - Wiley Online Library
A number of studies have indicated alterations of brain morphology in individuals with
autism spectrum disorder (ASD); however, how ASD influences the topological organization …

Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction

X Shi, C Lu, A Corman, A Nikish, Y Zhou… - The American Journal of …, 2023 - cell.com
Whole-exome sequencing of autism spectrum disorder (ASD) probands and unaffected
family members has identified many genes harboring de novo variants suspected to play a …

[引用][C] 84 16P11. 2 Patient-derived cerebral organoids show migration and synaptic defects

J Urresti, PM Losada, P Zhang, PD Negraes… - European …, 2019 - Elsevier

[HTML][HTML] Complement C4 is reduced in iPSC-derived astrocytes of autism spectrum disorder subjects

F Mansur, AL Teles e Silva, AKS Gomes… - International Journal of …, 2021 - mdpi.com
In recent years, accumulating evidence has shown that the innate immune complement
system is involved in several aspects of normal brain development and in …

Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour

V Verma, A Paul, A Amrapali Vishwanath… - Open …, 2019 - royalsocietypublishing.org
Normal brain development is highly dependent on the timely coordinated actions of genetic
and environmental processes, and an aberration can lead to neurodevelopmental disorders …

[HTML][HTML] Abnormal brain structure is associated with social and communication deficits in children with autism Spectrum disorder: a voxel-based morphometry analysis

MX Xu, XD Ju - Brain Sciences, 2023 - mdpi.com
Structural magnetic resonance imaging (sMRI) studies have shown abnormalities in the
brain structure of ASD patients, but the relationship between structural changes and social …