Anatomical differences in the mirror neuron system and social cognition network in autism

N Hadjikhani, RM Joseph, J Snyder… - Cerebral …, 2006 - academic.oup.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with impaired
social and emotional skills, the anatomical substrate of which is still unknown. In this study …

[HTML][HTML] Microglia at the tripartite synapse during postnatal development: Implications for autism spectrum disorders and schizophrenia

L Ferrucci, I Cantando, F Cordella, S Di Angelantonio… - Cells, 2023 - mdpi.com
Synapses are the fundamental structures of neural circuits that control brain functions and
behavioral and cognitive processes. Synapses undergo formation, maturation, and …

iPSC toolbox for understanding and repairing disrupted brain circuits in autism

S Chiola, NU Edgar, A Shcheglovitov - Molecular psychiatry, 2022 - nature.com
Over the past decade, tremendous progress has been made in defining autism spectrum
disorder (ASD) as a disorder of brain connectivity. Indeed, whole-brain imaging studies …

Function directs form of neuronal architecture

SX Chen, K Haas - Bioarchitecture, 2011 - Taylor & Francis
The human brain is an architectural marvel. The structure of each brain neuron and the
interconnected networks they create are critical to all brain functions, and structural …

Convergent microstructural brain changes across genetic models of autism spectrum disorder—A pilot study

PA Rowley, J Guerrero-Gonzalez, AL Alexander… - Psychiatry Research …, 2019 - Elsevier
Autism spectrum disorder (ASD) is a complex and genetically heterogeneous
neuropsychiatric disease affecting as many as 1 in 68 children. Large scale genetic …

Modeling synaptogenesis in schizophrenia and autism using human iPSC derived neurons

CW Habela, H Song, G Ming - Molecular and Cellular Neuroscience, 2016 - Elsevier
Schizophrenia (SCZ) and autism spectrum disorder (ASD) are genetically and
phenotypically complex disorders of neural development. Human genetic studies, as well as …

Hyper-excitability and hyper-plasticity disrupt cerebellar signal transfer in theIB2KO mouse model of autism

EU D'Angelo, T Soda, L Mapelli, F Locatelli, L Botta… - 2018 - europepmc.org
Autism spectrum disorders (ASD) are pervasive neurodevelopmental conditions that often
involve mutations affecting synaptic mechanisms. Recently, the involvement of cerebellum in …

[HTML][HTML] Sex differences in resting-state functional connectivity of the cerebellum in autism spectrum disorder

REW Smith, JA Avery, GL Wallace… - Frontiers in human …, 2019 - frontiersin.org
Autism spectrum disorder (ASD) is more prevalent in males than females, but the underlying
neurobiology of this sex bias remains unclear. Given its involvement in ASD, its role in …

Comprehensive behavioral phenotyping of a 16p11. 2 Del mouse model for neurodevelopmental disorders

JF Lynch III, SL Ferri, C Angelakos, H Schoch… - Autism …, 2020 - Wiley Online Library
The microdeletion of copy number variant 16p11. 2 is one of the most common genetic
mutations associated with neurodevelopmental disorders, such as Autism Spectrum …

Autism spectrum disorder: neuropathology and animal models

M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …