[HTML][HTML] Selective use of primate CD4 receptors by HIV-1
CJ Warren, NR Meyerson, O Dirasantha… - PLoS …, 2019 - journals.plos.org
Individuals chronically infected with HIV-1 harbor complex viral populations within their
bloodstreams. Recently, it has come to light that when these people infect others, the new …
bloodstreams. Recently, it has come to light that when these people infect others, the new …
Identification of owl monkey CD4 receptors broadly compatible with early-stage HIV-1 isolates
NR Meyerson, A Sharma, GK Wilkerson… - Journal of …, 2015 - Am Soc Microbiol
Most HIV-1 variants isolated from early-stage human infections do not use nonhuman
primate versions of the CD4 receptor for cellular entry, or they do so poorly. We and others …
primate versions of the CD4 receptor for cellular entry, or they do so poorly. We and others …
CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses
RM Russell, F Bibollet-Ruche, W Liu… - Proceedings of the …, 2021 - National Acad Sciences
Infection with human and simian immunodeficiency viruses (HIV/SIV) requires binding of the
viral envelope glycoprotein (Env) to the host protein CD4 on the surface of immune cells …
viral envelope glycoprotein (Env) to the host protein CD4 on the surface of immune cells …
A species-specific amino acid difference in the macaque CD4 receptor restricts replication by global circulating HIV-1 variants representing viruses from recent …
D Humes, S Emery, E Laws, J Overbaugh - Journal of virology, 2012 - Am Soc Microbiol
ABSTRACT HIV-1 replicates poorly in macaque cells, and this had hindered the
advancement of relevant nonhuman primate model systems for HIV-1 infection and …
advancement of relevant nonhuman primate model systems for HIV-1 infection and …
HIV entry: are all receptors created equal?
MA Goldsmith, RW Doms - nature immunology, 2002 - nature.com
HIV entry: are all receptors created equal? | Nature Immunology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …
you for visiting nature.com. You are using a browser version with limited support for CSS. To …
CD4 receptor diversity in chimpanzees protects against SIV infection
F Bibollet-Ruche, RM Russell, W Liu… - Proceedings of the …, 2019 - National Acad Sciences
Human and simian immunodeficiency viruses (HIV/SIVs) use CD4 as the primary receptor to
enter target cells. Here, we show that the chimpanzee CD4 is highly polymorphic, with nine …
enter target cells. Here, we show that the chimpanzee CD4 is highly polymorphic, with nine …
HIV entry into cells by CD4-independent mechanisms
PR Clapham, A McKnight, S Talbot… - Perspectives in drug …, 1996 - Springer
All HIV and SIV strains can enter cells by binding to cell-surface CD4. Therapeutics
designed to intervene in viral entry by blocking HIV attachment to CD4, may not work if entry …
designed to intervene in viral entry by blocking HIV attachment to CD4, may not work if entry …
Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1
D Kabat, SL Kozak, K Wehrly, B Chesebro - Journal of virology, 1994 - Am Soc Microbiol
CD4 is known to be an important receptor for human immunodeficiency virus type 1 (HIV-1)
infection of T lymphocytes and macrophages. However, the limiting steps in CD4-dependent …
infection of T lymphocytes and macrophages. However, the limiting steps in CD4-dependent …
A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV)
Pandemic HIV-1 (group M) emerged following the cross-species transmission of a simian
immunodeficiency virus from chimpanzees (SIVcpz) to humans. Primate lentiviruses …
immunodeficiency virus from chimpanzees (SIVcpz) to humans. Primate lentiviruses …
[HTML][HTML] Infection pressure in apes has driven selection for CD4 alleles that resist lentivirus (HIV/SIV) infection
CJ Warren, A Barbachano-Guerrero, VL Bauer… - eLife, 2024 - elifesciences.org
Simian immunodeficiency viruses (SIVs) comprise a large group of primate lentiviruses that
endemically infect African monkeys. HIV-1 spilled over to humans from this viral reservoir …
endemically infect African monkeys. HIV-1 spilled over to humans from this viral reservoir …