Strains of human immunodeficiency virus type 1 (HIV-1) that use the coreceptor CXCR4 (X4
strains) become laboratory adapted (LA) when selected for ability to replicate in leukemic T …

HIV infection of chimpanzees results in a chronic viremia unaccompanied by the ultimately
fatal immunodeficiency that marks HIV infection in man. We show here that expression of …

HIV-1, HIV-2 and SIV each bind to CD4 as the first step in virus entry. However, alternative
receptors may also be used. HIV-1 binds to glycolipids with terminal galactosylceramide …

Enveloped animal viruses enter cells via a series of steps that ultimately result in a fusion
reaction between the viral membrane and that of the host cell (Hernandez et al., 1996) …

Tremendous progress has been made in the past year in understanding the interaction
between HIV and its highly efficient route for infection of permissive cells, the CD4 antigen …

HIV is known to spread efficiently both in a cell-free state and from cell to cell, however the
relative importance of the cell-cell transmission mode in natural infection has not yet been …

Human immunodeficiency virus (HIV) entry into cells is initiated by the binding of its
envelope glycoprotein (Env) gp120 to receptor CD4. Antibodies that bind to epitopes …

More than 10 G protein-coupled receptors (GPCRs) have been reported to act as
coreceptors for entry of human and simian immunodeficiency viruses (HIV and SIV). We …

Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain
entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds …

During the late 1970's the application of hybridoma technology led to an explosion in the
discovery and characterization of proteins expressed at the surface of hematopoietic cells …