Podocyte injury, a major contributor to the pathogenesis of diabetic nephropathy, is caused
at least in part by the excessive generation of reactive oxygen species (ROS) …

Emodin has been demonstrated to possess multiple pharmacological activities. However,
emodin has also been reported to induce nephrotoxicity at high doses and with long‐term …

Oxidative stress is a major factor involved in the pathogenesis of renal ischemia/reperfusion
(I/R). Exogenous zinc (Zn) was suggested as a potent antioxidant; however, the mechanism …

Cisplatin is one of the synthetic cancer medicines with nephrotoxicity being one of its major
side effects. Past research shows that calcium dobesilate (CaD), as a vascular protective …

Diosmin (DM) is a naturally occurring flavone and has been found to possess numerous
therapeutic properties. In this study, we used DM as a protective agent against the …

Cisplatin‐induced nephrotoxicity persists as a clinical problem despite several supportive
measures to alleviate renal damage. Daidzein (DZ), a dietary isoflavone having antioxidant …

Clinical application of gentamicin (GM) is well known to be associated with the development
of acute kidney injury (AKI). This study was the first to investigate the possible protective …

Acute kidney injury (AKI) is a life-threatening complication that accompanies
rhabdomyolysis. Daidzein is a dietary isoflavone that has various biological activities. This …

Oxidative stress and inflammation are part and parcel of cisplatin‐induced nephrotoxicity.
The purpose of this work is to study the role of soy isoflavone constituent, daidzein, in …

Bergenin, isolated from Bergenia ligulata is a potent antioxidant and antilithiatic agent.
Present work was designed to establish the biochemical role of bergenin on mitochondrial …