Currently, chronic kidney disease (CKD) is one of the most common diseases; it is also a
serious threat to human health due to its high mortality, and its treatment is still a major …

Aim To investigate the efficacy of zinc oxide nanoparticles (ZnO-NPs) and/or milrinone (MIL)
on renal ischemia/reperfusion injury (I/RI) in rats and their possible underlying mechanisms …

Introduction Cisplatin, an anti-cancer drug is used to treat a wide range of solid tumors.
Nevertheless, nephrotoxicity is the major adverse effect that restricts its clinical application …

Background: Some researches revealed that mitochondrial dysfunction is associated with
various kidney injury. However, the role of mitochondrial dysfunction in the pathogenesis of …

Background The important roles of liver and kidney in the elimination of injurious chemicals
make them highly susceptible to the noxious activities of various toxicants including cobalt …

Cancer chemotherapy drug cisplatin is known for its nephrotoxicity. The aim of this study is
to investigate whether Epigallocatechin 3-Gallate (EGCG) can reduce cisplatin mediated …

Oxalate is a small compound found in certain plant-derived foods and is a major component
of calcium oxalate (CaOx) kidney stones. Individuals that consume oxalate enriched meals …

Cyclophosphamide [CP], as alkylating agents has side effects such as nephrotoxicity.
Cerium oxide nanoparticles [nanoceria; NC], as an antioxidant, are effective at reduction …

Hypercholesterolemia can aggravate contrast‐induced acute kidney injury, and the
exacerbation of renal tubular epithelial cell (RTEC) injury is a major cause. However, the …

Diclofenac, a non-steroidal anti-inflammatory drug, reportedly targets mitochondria and
induces nephrotoxicity via reactive oxygen species. However, there are few detailed reports …