[PDF][PDF] The role of vitamin E in the prevention of zoledronic acid-induced nephrotoxicity in rats: a light and electron microscopy study
Results: For group 2, the p-values are all< 0.001 for Paller score, epitelial thickness, and
basal membrane thickness. For group 3 (ZA+ Vit. E), the p-values are< 0.001 for Paller …
basal membrane thickness. For group 3 (ZA+ Vit. E), the p-values are< 0.001 for Paller …
Manganese-induced nephrotoxicity is mediated through oxidative stress and mitochondrial impairment
Manganese (Mn) is an essential element that is incorporated in various metabolic pathways
and enzyme structures. On the other hand, a range of adverse effects has been described in …
and enzyme structures. On the other hand, a range of adverse effects has been described in …
Licorice extracts attenuate nephrotoxicity induced by brucine through suppression of mitochondria apoptotic pathway and STAT3 activation
M Zhang, C Wang, H Cai, J Wen, P Fang - Current Medical Science, 2019 - Springer
Licorice, one of the most widely used medicinal herbs in East Asia, has effects such as anti-
inflammation, antioxidant, and detoxifying. This study aimed to evaluate the protective effect …
inflammation, antioxidant, and detoxifying. This study aimed to evaluate the protective effect …
Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid
V Chander, D Singh, K Chopra - Pharmacology, 2005 - karger.com
The occurrence of acute renal failure (ARF) following rhabdomyolysis has been put at
between 10 and 40% of cases, and accounts for between 3 and 15% of all cases of ARF …
between 10 and 40% of cases, and accounts for between 3 and 15% of all cases of ARF …
[HTML][HTML] α-Bisabolol attenuates doxorubicin induced renal toxicity by modulating NF-κB/MAPK signaling and caspase-dependent apoptosis in rats
S Arunachalam, MF Nagoor Meeran… - International journal of …, 2022 - mdpi.com
Doxorubicin (DOX) is a well-known and effective antineoplastic agent of the anthracycline
family. But, multiple organ toxicities compromise its invaluable therapeutic usage. Among …
family. But, multiple organ toxicities compromise its invaluable therapeutic usage. Among …
[HTML][HTML] Study of the protective effects of cyanocobalamin on methotrexate induced nephrotoxicity in rats
RQ Abdulwahhab, SMA Alabdali - F1000Research, 2022 - ncbi.nlm.nih.gov
Background: Methotrexate (MTX) is a chemotherapeutic drug, used mainly in many
cancerous stages, inflammatory and auto-immune diseases, but its use has been limited by …
cancerous stages, inflammatory and auto-immune diseases, but its use has been limited by …
[HTML][HTML] Rosinidin protects against cisplatin-induced nephrotoxicity via subsiding proinflammatory and oxidative stress biomarkers in rats
Background: Rosinidin is a flavonoid anthocyanin pigmentation found in shrub flowers such
as Catharanthus roseus and Primula rosea. The molecular docking studies predicted that …
as Catharanthus roseus and Primula rosea. The molecular docking studies predicted that …
Mitochondria-Targeted Antioxidant Mito-Tempo Protects Against Aldosterone-Induced Renal Injury In Vivo
W Ding, T Liu, X Bi, Z Zhang - Cellular Physiology and Biochemistry, 2017 - karger.com
Abstract Background/Aims: Growing evidence suggests mitochondrial dysfunction (MtD) and
the Nlrp3 inflammasome play critical roles in chronic kidney disease (CKD) progression. We …
the Nlrp3 inflammasome play critical roles in chronic kidney disease (CKD) progression. We …
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity
Aim Gentamicin (GM) is an aminoglycoside antibiotic effectively used for severe/life-
threatening infections. However, the clinical application of GM is limited by nephrotoxic side …
threatening infections. However, the clinical application of GM is limited by nephrotoxic side …
Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin
SH Avila-Rojas, OE Aparicio-Trejo… - Food and Chemical …, 2020 - Elsevier
Curcumin has protective effects in several acute kidney injury models, including that induced
by potassium dichromate (K 2 Cr 2 O 7). The protective effect of curcumin in this …
by potassium dichromate (K 2 Cr 2 O 7). The protective effect of curcumin in this …