New advances in the treatment of acute myocardial infarction involve novel signalling
pathways and cellular progeny. In this sense, regeneration is a novel tool that would …

The heart is essential for realizing the distribution of oxygen and nutrients throughout the
body. Therefore, the heart is the first organ to develop and is already functional in its most …

The Wilms' tumour gene, WT1, encodes a zinc-finger transcription factor that is inactivated in
a subset of Wilms' tumours. Mutation analysis in human patients and genetic experiments in …

The Wilms tumor suppressor gene (Wt1) encodes a C2H2-type zinc-finger transcription
factor that participates in transcriptional regulation, RNA metabolism, and protein–protein …

Various cell types are involved in the healing process after myocardial infarction (MI).
Besides cardiac resident cells (such as cardiomyocytes, fibroblasts and endothelial cells) …

Abstract The transcription factor Wilms' Tumor-1 (WT1) is essential for cardiac development.
Deletion of Wt1 in mice results in disturbed epicardial and myocardial formation and lack of …

Nearly three decades ago, the Wilms' tumor suppressor Wt1 was identified as a crucial
regulator of heart development. Wt1 is a zinc finger transcription factor with multiple …

The embryonic epicardium is an important source of cardiovascular precursor cells and
paracrine factors that are required for adequate heart formation. Signaling pathways …

Following myocardial infarction, wound healing takes place in the infarct area where the non-
viable cardiac tissue is replaced by a scar. Inadequate wound healing or insufficient …

of potential clinical relevance. Tß4 is expressed in many different organs and has direct
effects on the actin cytoskeleton and the balance between monomeric and polymerized …