Hydrogen peroxide has adverse effects on human sperm quality parameters, induces apoptosis, and reduces survival

DA Pujianto, M Oktarina… - Journal of human …, 2021 - journals.lww.com
Background: One of the causes of male fertility disorders is the exposure of oxidative stress
on the human sperm. Understanding the mechanism of disturbance is important to develop …

[HTML][HTML] Sperm viability, apoptosis, and intracellular reactive oxygen species levels in human spermatozoa before and after induction of oxidative stress

RZ Mahfouz, SS du Plessis, N Aziz, R Sharma… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To investigate sperm viability, incidence of apoptosis, and intracellular basal
and induced reactive oxygen species (ROS) in sperm fractions. DESIGN: Prospective …

[HTML][HTML] Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa

NK Duru, M Morshedi, S Oehninger - Fertility and sterility, 2000 - Elsevier
Objective: To evaluate the effects of oxidative stress on DNA and plasma membrane integrity
of human spermatozoa. Design: Prospective cohort study. Setting: University-based, tertiary …

[HTML][HTML] Increase of oxidative stress in human sperm with lower motility

SH Kao, HT Chao, HW Chen, TIS Hwang, TL Liao… - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To investigate the causal role of oxidative-stress status on human sperm
motility. DESIGN: To demonstrate that sperm with higher oxidative damage have a lower …

[HTML][HTML] Sperm oxidative stress is detrimental to embryo development: a dose-dependent study model and a new and more sensitive oxidative status evaluation

LS De Castro, PM De Assis, AFP Siqueira… - … Medicine and Cellular …, 2016 - hindawi.com
Our study aimed to assess the impact of sperm oxidative stress on embryo development by
means of a dose-dependent model. In experiment 1, straws from five bulls were subjected to …

Zinc protects sperm from being damaged by reactive oxygen species in assisted reproduction techniques

J Wu, S Wu, Y Xie, Z Wang, R Wu, J Cai, X Luo… - Reproductive …, 2015 - Elsevier
The aim of this study was to explore the effect of zinc on hydrogen peroxide-induced sperm
damage in assisted reproduction techniques. First, sperms were selected from semen …

Oxidative stress is associated with reduced sperm motility in normal semen

W Kurkowska, A Bogacz… - American journal of …, 2020 - journals.sagepub.com
Infertility is among the most serious medical problems worldwide. Male factors contribute to
40%–50% of all infertility cases, and approximately 7% of men worldwide are affected by …

Role of reactive oxygen species in male reproduction

S Fatima - Novel Prospects in Oxidative and Nitrosative Stress, 2018 - books.google.com
The production of reactive oxygen species (ROS) is a normal physiological event in the male
germ line. ROS are a double-edged sword, despite its role as key signaling molecules in …

Use of hydrogen peroxide to assess the sperm susceptibility to oxidative stress in subjects presenting a normal semen profile

MM Misro, L Choudhury, K Upreti… - … journal of andrology, 2004 - Wiley Online Library
Human sperm susceptibility to oxidative stress is vital as it affects various characteristics of
sperm function. In the present study, we report a simple, sensitive and quick method of …

Assessment of human sperm function after hydrogen peroxide exposure: development of a vaginal contraceptive

SP Chaki, MM Misro - Contraception, 2002 - Elsevier
The reactive oxygen species (ROS) that is most damaging to human spermatozoa is
hydrogen peroxide. Using an artificial medium Ham's F-10, we have evaluated the effect of …