Biological activities of paeonol in cardiovascular diseases: a review

S Vellasamy, D Murugan, R Abas, A Alias, WY Seng… - Molecules, 2021 - mdpi.com
Paeonol is a naturally existing bioactive compound found in the root bark of Paeonia
suffruticosa and it is traditionally used in Chinese medicine for the prevention and …

[HTML][HTML] Paeonol for the treatment of atherosclerotic cardiovascular disease: A pharmacological and mechanistic overview

M Wu, Z Yu, X Li, X Zhang, S Wang, S Yang… - Frontiers in …, 2021 - frontiersin.org
With improvement in living standards and average life expectancy, atherosclerotic
cardiovascular disease incidences and mortality have been increasing annually. Paeonia …

A review on therapeutical potential of paeonol in atherosclerosis

W Yu, I Ilyas, N Aktar, S Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
The morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD) is increasing
year by year. Cortex Moutan is a traditional Chinese medicinal herb that has been widely …

Review of the protective mechanism of Paeonol on cardiovascular disease

C Yang, J Cheng, Q Zhu, Q Pan, K Ji… - … Design, Development and …, 2023 - Taylor & Francis
Cardiovascular disease (CVD) is one of the leading causes of death in the world. Paeonol
(Pae) is a phenolic component extracted from peony bark, peony root and Xu Changqing …

Beneficial effects exerted by paeonol in the management of atherosclerosis

L Lu, Y Qin, C Chen, X Guo - Oxidative medicine and cellular …, 2018 - Wiley Online Library
Atherosclerosis, a chronic luminal stenosis disorder occurred in large and medium arteries,
is the principle pathological basis of cardiovascular diseases with the highest morbidity and …

Paeonol: pharmacological effects and mechanisms of action

L Zhang, D Li, L Liu - International Immunopharmacology, 2019 - Elsevier
Paeonia suffruticosa possesses various medicinal benefits and has been used extensively
in traditional oriental medicine for thousands of years. Paeonol is the main component …

[HTML][HTML] Protective effects of paeoniflorin on cardiovascular diseases: A pharmacological and mechanistic overview

X Li, C Sun, J Zhang, L Hu, Z Yu, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background and ethnopharmacological relevance: The morbidity and mortality of
cardiovascular diseases (CVDs) are among the highest of all diseases, necessitating the …

Paeonol from Paeonia suffruticosa prevents TNF-α-induced monocytic cell adhesion to rat aortic endothelial cells by suppression of VCAM-1 expression

LL Pan, M Dai - Phytomedicine, 2009 - Elsevier
Paeonol (2′-hydroxy-4′-methoxyacetophenone), the main active compound of the radix of
Paeonia suffruticosa, has been reported to have a beneficial effect in prevention and …

Paeonol attenuates high-fat-diet-induced atherosclerosis in rabbits by anti-inflammatory activity

H Li, M Dai, W Jia - Planta medica, 2009 - thieme-connect.com
Abstract Cortex Moutan (Paeonia suffruticosa Andrews, Ranunculaceae) has several uses
in traditional medicine, such as analgesic, antipyretic, and anti-inflammatory applications …

Paeonol suppresses oxidized low-density lipoprotein induced endothelial cell apoptosis via activation of LOX-1/p38MAPK/NF-κB pathway

M Bao, Y Zhang, H Zhou - Journal of ethnopharmacology, 2013 - Elsevier
Paeonol is an active compound isolated from traditional Chinese medicine, and has been
shown to have anti-atherosclerosis, anti-inflammatory, antioxidant effects. The present …