Advanced lung imaging and lung function testing in Ataxia-Telangiectasia

S Alenazi - 2022 - eprints.nottingham.ac.uk
Although a CT scan provides high-resolution images for lung, it involves use of ionising
radiation, which in some patient groups might increase risk of cancer, for example, it …

Early experience of oxygen enhanced magnetic resonance imaging (OE-MRI) in ataxia telangiectasia (AT)

A Prayle, M Tibiletti, C Youle, S Safavi, S Alenazi… - 2018 - Eur Respiratory Soc
Ataxia-Telangiectasia (AT) is characterised by progressive ataxia, immunodeficiency,
malignancy and chronic lung infection. Respiratory disease and cancer are leading causes …

Non invasive assessment of lung disease in ataxia telangiectasia by high-field magnetic resonance imaging

S Montella, C Mollica, A Finocchi, A Pession… - Journal of clinical …, 2013 - Springer
Purpose A sensitive imaging technique that assesses ataxia telangiectasia (AT) lung
disease without ionizing radiation is highly desirable. We designed a study to evaluate lung …

Synopsis from expanding applications of pulmonary MRI in the clinical evaluation of lung disorders: Fleischner Society position paper

ML Schiebler, G Parraga, WB Gefter, B Madore, KS Lee… - Chest, 2021 - journal.chestnet.org
This is a synopsis from a recently published Fleischner Society Position Paper entitled
“Expanding Applications of Pulmonary MRI in the Clinical Evaluation of Lung Disorders.” 1 …

State-of-the-art MR Imaging for Thoracic Diseases

Y Tanaka, Y Ohno, S Hanamatsu, Y Obama… - … Resonance in Medical …, 2022 - jstage.jst.go.jp
Since thoracic MR imaging was first used in a clinical setting, it has been suggested that MR
imaging has limited clinical utility for thoracic diseases, especially lung diseases, in …

Reversible airway obstruction in children with ataxia telangiectasia

Y Berkun, D Vilozni, Y Levi, S Borik… - Pediatric …, 2010 - Wiley Online Library
Introduction Lung disease is a significant cause of the short life span of ataxia telangiectasia
(A‐T) patients. Objective lung function measurements are difficult to achieve in A‐T. Aim To …

Pulmonary function in adolescents with ataxia telangiectasia

S McGrath‐Morrow, M Lefton‐Greif… - Pediatric …, 2008 - Wiley Online Library
Introduction Pulmonary complications are common in adolescents with ataxia telangiectasia
(A‐T), however objective measurements of lung function may be difficult to obtain because …

Lung disease in ataxia‐telangiectasia

L Bott, JP Lebreton, C Thumerelle, JC Cuvellier… - Acta …, 2007 - Wiley Online Library
Ataxia‐telangiectasia (AT) is a multi‐systemic disease caused by mutational inactivation of
the ATM gene. We report a retrospective study of lung disease in 15 patients. Patients and …

Pulmonary function in children and young adults with ataxia telangiectasia

SA McGrath‐Morrow, HM Lederman… - Pediatric …, 2014 - Wiley Online Library
Background Pulmonary disease contributes to significant morbidity and mortality in people
with ataxia telangiectasia (A‐T). To determine the association between age and lung …

Evaluation and management of pulmonary disease in ataxia‐telangiectasia

SA McGrath‐Morrow, WA Gower… - Pediatric …, 2010 - Wiley Online Library
Abstract Ataxia‐telangiectasia (A‐T) is a rare autosomal recessive disorder caused by
mutations in the ATM gene, resulting in faulty repair of breakages in double‐stranded DNA …