Chromium malate alleviates high-glucose and insulin resistance in L6 skeletal muscle cells by regulating glucose uptake and insulin sensitivity signaling pathways

W Feng, Y Ding, W Zhang, Y Chen, Q Li, W Wang… - Biometals, 2018 - Springer
Previous study revealed that chromium malate improved the regulation of fasting blood
glucose and insulin resistance in type 2 diabetic rats. In this study, the effect of chromium …

Improvement of high-glucose and insulin resistance of chromium malate in 3T3-L1 adipocytes by glucose uptake and insulin sensitivity signaling pathways and its …

W Feng, Y Liu, F Fei, Y Chen, Y Ding, M Yan, Y Feng… - RSC …, 2019 - pubs.rsc.org
Previous study has revealed that chromium malate could improve insulin resistance and the
regulation of fasting blood glucose in type 2 diabetic rats. This study was designed to …

Chromium supplementation enhances insulin signalling in skeletal muscle of obese KK/HlJ diabetic mice

WY Chen, CJ Chen, CH Liu… - Diabetes, Obesity and …, 2009 - Wiley Online Library
Aim: Chromium is an essential nutrient required for glucose and lipid metabolism.
Laboratory and clinical evidences indicate that chromium supplementation may improve …

Type 2 diabetic rats on diet supplemented with chromium malate show improved glycometabolism, glycometabolism-related enzyme levels and lipid metabolism

W Feng, T Zhao, G Mao, W Wang, Y Feng, F Li… - PLoS …, 2015 - journals.plos.org
Our previous study showed that chromium malate improved the regulation of blood glucose
in mice with alloxan-induced diabetes. The present study was designed to evaluate the …

Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK

Y Wang, M Yao - The Journal of Nutritional Biochemistry, 2009 - Elsevier
Chromium picolinate (CrPic) has been discovered as a supplemental or alternative
medication for type 2 diabetes, but its mechanism of action is not well understood. The …

Chromium-containing traditional Chinese medicine, Tianmai Xiaoke Tablet improves blood glucose through activating insulin-signaling pathway and inhibiting PTP1B …

Q Zhang, X Xiao, M Li, W Li, M Yu, H Zhang… - Journal of Integrative …, 2014 - Elsevier
OBJECTIVE Chromium is an essential mineral that is thought to be necessary for normal
glucose homeostasis. Numerous studies give evidence that chromium picolinate can …

Regulation of chromium on gene expression of skeletal muscles in diabetic rats

YT Wu, Z Sun, SP Che, X Wang, Y Wang… - Wei Sheng yan jiu …, 2005 - europepmc.org
Objective To study the regulation of chromium on gene expression related to metabolism of
skeletal muscles in diabetic rats. Methods Male Wistar rats were assigned to three groups …

Antagonizing Effects of Chromium Against Iron-Decreased Glucose Uptake by Regulating ROS-Mediated PI3K/Akt/GLUT4 Signaling Pathway in C2C12

L Fan, L Li, Y Zhao, Y Zhao, F Wang, Q Wang… - Biological trace element …, 2024 - Springer
To investigate the effect of chromium and iron on glucose metabolism via the
PI3K/Akt/GLUT4 signaling pathway. Skeletal muscle gene microarray data in T2DM …

Chromium improves glucose uptake and metabolism through upregulating the mRNA levels of IR, GLUT4, GS, and UCP3 in skeletal muscle cells

W Qiao, Z Peng, Z Wang, J Wei, A Zhou - Biological trace element …, 2009 - Springer
The aim of this study was to evaluate the impact of three different chromium forms as
chromic chloride (CrCl), chromium picolinate (CrPic), and a newly synthesized complex of …

Effects of chromium malate on glycometabolism, glycometabolism‐related enzyme levels and lipid metabolism in type 2 diabetic rats: A dose–response and curative …

W Feng, G Mao, Q Li, W Wang, Y Chen… - Journal of diabetes …, 2015 - Wiley Online Library
Abstract Aims/Introduction The present study was designed to evaluate the effect of
chromium malate on glycometabolism, glycometabolism‐related enzyme levels and lipid …