An expert opinion on the role of the Rosuvastatin/Amlodipine single pill fixed dose combination in cardiovascular prevention

G Gallo, R Sarzani, AFG Cicero, S Genovese… - High Blood Pressure & …, 2023 - Springer
Current cardiovascular disease prevention strategies are based on the management of
cardiovascular risk as a continuum, redefining the therapeutic goals for each individual …

Lisinopril, Amlodipine, Rosuvastatin as a Novel Fixed Combination in the Fight Against Cardiovascular Disease

AE Semenova, IV Sergienko - Kardiologiia, 2017 - europepmc.org
The prevalence of multicomponent therapy in treatment of cardiovascular diseases makes
fixed combinations of drugs very useful. The fixed combination of rosuvastatin with ACE …

Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an …

FDR Hobbs, G Gensini, GBJ Mancini… - International journal of …, 2006 - Elsevier
BACKGROUND: In order to prevent cardiovascular events, it is essential to effectively
manage overall risk of cardiovascular disease. However, despite guideline …

Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? The single pill of amlodipine …

FD Richard Hobbs - Vascular health and risk management, 2007 - Taylor & Francis
In order to prevent cardiovascular events, it is essential to effectively manage overall risk of
cardiovascular disease. However, despite guideline recommendations to this effect, current …

Combining antihypertensive and antihyperlipidemic agents–optimizing cardiovascular risk factor management

J Zamorano, J Edwards - Integrated blood pressure control, 2011 - Taylor & Francis
Clinical guidelines now recognize the importance of a multifactorial approach to managing
cardiovascular (CV) risk. This idea was taken a step further with the concept of the Polypill™ …

Amlodipine/atorvastatin: the first cross risk factor polypill for the prevention and treatment of cardiovascular disease

WH Frishman, AL Zuckerman - Expert Review of Cardiovascular …, 2004 - Taylor & Francis
In 2002, the World Health Organization estimated that over 58% of cardiovascular disease in
North America is due to 'both blood pressure and cholesterol higher than optimal' …

Fixed combination of amlodipine and atorvastatin in cardiovascular risk management: patient perspectives

M Devabhaktuni, S Bangalore - Vascular health and risk …, 2009 - Taylor & Francis
Hypertension and dyslipidemia are two of the most commonly co-occurring cardiovascular
risk factors which together cause an increase in coronary heart disease-related events that …

Randomized, multicenter, parallel, open, phase 4 study to compare the efficacy and safety of rosuvastatin/amlodipine polypill versus atorvastatin/amlodipine polypill in …

HW Jung, CY Kim, SP Hong, HJ Bae… - The Journal of …, 2023 - Wiley Online Library
The authors performed this study to investigate the efficacy and safety of a rosuvastatin
(RSV)/amlodipine (AML) polypill compared with those of atorvastatin (ATV)/AML polypill. We …

Cardiovascular risk reduction: what do recent trials with rosuvastatin tell us?

G Fabbri, AP Maggioni - Advances in therapy, 2009 - Springer
Abundant evidence from large-scale clinical trials supports the importance of lowering low-
density lipoprotein cholesterol (LDL-C) to decrease the risk of cardiovascular disease (CVD) …

[HTML][HTML] A fixed-dose lisinopril+ amlodipine+ rosuvastatin combination: prospects for its use in patients with hypertension and concomitant dyslipidemia

VI Podzolkov, AE Bragina, KK Osadchiy - Terapevticheskii arkhiv, 2017 - edgccjournal.org
In Russia, target blood pressure (BP) levels are achieved in only 14.4% of men and in
30.9% of women. The need for combination therapy of hypertension is as high as 70.7 …