We investigated the effects of ovariectomy (OVX) and 17β-estradiol (0.18 mg per pellet)
treatment on spatial learning and memory, hippocampal beta amyloid (Aβ) levels, and …

Research indicates that female risk of developing Alzheimer's disease (AD) is greater than
that of males. Moderate reduction of calorie intake, known as calorie restriction (CR) …

Introduction Females may have greater susceptibility to Alzheimer's disease (AD)‐
pathology. We examined the effect of sex on pathology, neurodegeneration, and memory in …

Background: Alzheimer's disease (AD) is characterized by a high etiological and clinical
heterogeneity, which has obscured the diagnostic and treatment efficacy, as well as limited …

Background The pathological hallmarks of Alzheimer's disease (AD) involve alterations in
the expression of numerous genes associated with transcriptional levels, which are …

Quantitative microanalysis of brains from patients with Alzheimer's disease (AD) find
neuronal loss and neuroinflammation in structures that control cognitive function. Though …

Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases
in the US alone (Alzheimer's Association,). Clinically, AD is defined by the presence of …

The impact of sex and menopausal status in Alzheimer's disease remains understudied
despite increasing evidence of greater female risk, particularly in APOE4 carriers. Utilizing …

No model fully recapitulates the neuropathology of Alzheimer's disease (AD). Although the
triple‐transgenic mouse model of AD (3xTg‐AD) expresses Aβ plaques and tau‐laden …

Aging and sex are major risk factors for developing late-onset Alzheimer's disease.
Compared to men, women experience worse neuropathological burden and cognitive …