Silkworm was the first domesticated insect and has important economic value. It has also
become an ideal model organism with applications in genetic and expression studies. In …

The domesticated silkworm, Bombyx mori, is an economically important insect that
synthesizes large amounts of silk proteins in its silk gland to make cocoons. In recent years …

Genetically engineered silkworms have been widely used to obtain silk with modified
characteristics especially by introducing spider silk genes. However, these attempts are still …

Evolution has produced some remarkable creatures, of which silk gland is a fascinating
organ that exists in a variety of insects and almost half of the 34,000 spider species. The …

Genome editing is a powerful tool for the functional analysis of targeted genes. We have
previously found that a novel knock-in system, precise integration into target chromosome …

The silkworm Bombyx mori is a valuable insect that synthesizes bulk amounts of fibroin
protein in its posterior silk gland (PSG) and weaves these proteins into silk cocoons. The …

Bombyx mori (silkworm) silk proteins are being utilized as unique biomaterials for medical
applications. Chemical modification or post-conjugation of bioactive ligands expand the …

Bombyx mori silk fibroin is a natural protein material characterized by mechanical toughness
and biocompatibility, which makes it a promising candidate for the development of …

We developed an efficient strategy that combines a method for the post-integration
elimination of all transposon sequences, a site-specific recombination system and an …

Cre-mediated recombination is widely used to manipulate defined genes spatiotemporally in
vivo. The present study evaluated the Cre/loxP system in Bombyx mori by establishing two …