BACKGROUND Congenital heart diseases (CHDs) represent about 0.8% to 1% livebirths. 1
This value is progressively changing with the rapid advances in tools applied in prenatal …

The genetic etiologies of multiple cardiovascular disorders have been identified recently. For
the most part, familial cardiomyopathic, vascular, or arrhythmogenic disorders have been …

It is important to understand the genetic causes and influences on the development of
congenital heart defects for us to advance the fields of pediatric cardiology and adult …

Congenital heart disease is the most common birth defect, and because of major advances
in medical and surgical management, there are now more adults living with congenital heart …

Congenital malformations of the heart are the most common of all birth defects. Traditionally,
a multifactorial model combining genetic predisposition with environmental influence has …

In spite of the amazing success during the past half century in diagnosis and treatment of
congenital heart disease, very little is known of its cause. However, a genetic cause has …

Clinically relevant congenital heart disease affects 1% of all live births. It is the leading
cause of birth defects–related death in the United States, claiming more than 6000 lives per …

Congenital heart disease (CHD) has an overall incidence of nearly 1% in the general
population (excluding bicuspid aortic valve) and is a major cause of morbidity and mortality …

Congenital heart disease (CHD) is the most common major congenital anomaly with an
incidence of∼ 1% of live births and is a significant cause of birth defect–related mortality …

Congenital heart disease (CHD) is the most common type of birth defect. Despite the many
advances in the understanding of cardiac development and the identification of many genes …