Impaired angiogenesis is crucial for impeding the wound healing process in diabetic foot
ulcers (DFUs). In this study, we found that Angelica dahurica (A. dahurica) stimulated …

Impaired angiogenesis is one of the crucial factors that impede the wound healing process
in diabetic foot ulcers (DFUs). In this study, we found that 20 (S)-protopanaxadiol (PPD), an …

Wound therapy remains a clinical challenge due to the complexity of healing pathology and
high demand of achieving functional and aesthetically satisfactory scars. Newly formed …

Diabetic foot ulcers are a major health‐care burden worldwide. One primary cause of the
delayed wound healing in diabetic patients is impaired function of the hypoxia‐inducible …

Diabetic foot ulcer is closely associated with peripheral vascular disease. Enhancement of
tissue oxidative stress, reduction of nitric oxide (NO) and angiogenic growth factors, and …

Nonhealing chronic wounds on foot induced by diabetes is a complicated pathologic
process. They are mainly caused by impaired neovascularization, neuropathy, and …

As one of the most frequent diabetic complications, diabetic foot ulcer (DFU) can cause limb
ischemia or even amputation. Paeoniflorin (PF) has been reported to possess many kinds of …

Background Hypoxia-inducible factor 1α is the central regulator of the hypoxia-induced
response which results in the up-regulation of angiogenic factors. Its activity is under precise …

Wound healing requires the essential participation of fibroblasts, which is impaired in
diabetic foot ulcers (DFU). Notoginsenoside Ft1 (Ft1), a saponin from Panax notoginseng …

Abnormal angiogenesis plays an important role in impaired wound healing and
development of chronic wounds in diabetes mellitus. Angelica dahurica radix is a common …