Neoadjuvant versus adjuvant systemic therapy for early-stage non-small cell lung cancer: the changing landscape due to immunotherapy

AO John, N Ramnath - The Oncologist, 2023 - academic.oup.com
Non-small cell lung cancer (NSCLC) remains a major cause of morbidity and mortality
worldwide. One-third of NSCLC patients present with surgically resectable, non-metastatic …

[HTML][HTML] Neoadjuvant and adjuvant immunotherapy in non-small cell lung cancer—Clinical trials experience

I Chmielewska, K Stencel, E Kalinka, R Ramlau… - Cancers, 2021 - mdpi.com
Simple Summary Surgical resection remains the gold standard of early-stage non-small cell
lung cancer (NSCLC) treatment. However, only a minority of resected patients remain …

Safety and efficacy of neoadjuvant immune checkpoint inhibitor therapy in patients with resectable non-small-cell lung cancer: a systematic review

Z Zhao, Y Gao, QI Xue, S Gao, J He - Targeted oncology, 2021 - Springer
Background Non-small-cell lung cancer (NSCLC) accounts for most new diagnoses of lung
cancer, with high morbidity and mortality worldwide. Immune checkpoint inhibitor (ICI) …

[HTML][HTML] Role and impact of immune checkpoint inhibitors in neoadjuvant treatment for NSCLC

A Friedlaender, J Naidoo, GL Banna, G Metro… - Cancer treatment …, 2022 - Elsevier
In the last decade, immune-checkpoint inhibitors (ICIs) have become the backbone of
therapy in advanced, non-oncogene driven, non-small cell lung cancer (NSCLC). More …

[HTML][HTML] Neoadjuvant immunotherapy in non-small cell lung cancer: a narrative review on mechanisms, efficacy and safety

L Shao, G Lou - Journal of Thoracic Disease, 2022 - ncbi.nlm.nih.gov
Methods Relevant articles for this review were retrieved from Google Scholar, Clinicaltrials.
gov., and PubMed using the terms “non-small-cell lung cancer”,“NSCLC”,“neoadjuvant”,“ …

[HTML][HTML] Integrating immune checkpoint inhibitors and targeted therapies in the treatment of early stage non-small cell lung cancer: a narrative review

A Ortega-Franco, V Calvo, F Franco… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Prognosis of early stage non-small cell lung cancer (eNSCLC) is poor even when treated
radically with surgery and (neo) adjuvant chemotherapy (Cht). The discovery of tyrosine …

[HTML][HTML] The immunotherapeutic landscape in non–small cell lung cancer and its surgical horizons

KE Rhodin, AJ Rucker, NE Ready, TA D'Amico… - The Journal of Thoracic …, 2020 - Elsevier
Lung cancer continues to be a leading cause of cancer-related death worldwide. Despite
tremendous advances in surgical technique, chemotherapy regimens, radiation, and …

[HTML][HTML] Current approaches to neoadjuvant immunotherapy in resectable non-small cell lung cancer

J Parekh, K Parikh, JE Reuss, A Friedlaender… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review For decades, early-stage resectable non-small cell lung cancer
(NSCLC), while potentially curable, has been marred by unacceptably high recurrence …

[HTML][HTML] Neoadjuvant immune checkpoint inhibitors in resectable non-small-cell lung cancer: a systematic review

EB Ulas, C Dickhoff, FL Schneiders, S Senan, I Bahce - Esmo Open, 2021 - Elsevier
Background The neoadjuvant use of immune checkpoint inhibitors (ICIs) in resectable non-
small-cell lung cancer (NSCLC) is currently an area of active ongoing research. The place of …

Perioperative systemic therapy for resectable non–small cell lung cancer

B Muthusamy, PD Patil, NA Pennell - Journal of the National …, 2022 - jnccn.org
Despite remarkable treatment advancements in patients with advanced non–small cell lung
cancer (NSCLC), recurrence rates for those with resectable, early-stage disease remains …