[PDF][PDF] Serum levels of spexin and kisspeptin negatively correlate with obesity and insulin resistance in women

PA Kołodziejski, E Pruszyńska-Oszmałek… - Physiological …, 2018 - biomed.cas.cz
Spexin (SPX) and kisspeptin (KISS) are novel peptides relevant in the context of regulation
of metabolism, food intake, puberty and reproduction. Here, we studied changes of serum …

Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals

F Andreozzi, GC Mannino, E Mancuso, R Spiga… - PloS one, 2017 - journals.plos.org
To evaluate if plasma kisspeptin concentrations are associated with insulin secretion, as
suggested by recent in vitro studies, independently of confounders. 261 nondiabetic …

Role of kisspeptin in polycystic ovary syndrome (PCOS)

O Emekci Ozay, AC Ozay, B Acar… - Gynecological …, 2016 - Taylor & Francis
Objective: Due to the complex relationship between kisspeptin and the hypothalamic-
pituitary-gonadal axis, the study was planned to measure the kisspeptin levels in polycystic …

Plasma kisspeptin and ghrelin levels are independently correlated with physical activity in patients with anorexia nervosa

T Hofmann, U Elbelt, V Haas, A Ahnis, BF Klapp… - Appetite, 2017 - Elsevier
While physical hyperactivity represents a frequent symptom of anorexia nervosa and may
have a deleterious impact on the course of the disease, the underlying mechanisms are …

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Spexin: Its role, regulation, and therapeutic potential in the hypothalamus

A Tran, W He, JTC Chen, DD Belsham - Pharmacology & therapeutics, 2022 - Elsevier
Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …

Effects of kisspeptin on pathogenesis and energy metabolism in polycystic ovarian syndrome (PCOS)

T Wang, S Han, W Tian, M Zhao… - Gynecological …, 2019 - Taylor & Francis
Kisspeptin has been shown to participate in the regulation of pituitary hormone secretion
and energy metabolism. In PCOS patients, there are disorders in pituitary hormone secretion …

The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans

C Izzi‐Engbeaya, AN Comninos… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and
appetite in humans. Materials and methods In 15 healthy men (age: 25.2±1.1 years; BMI …

[HTML][HTML] Plasma metastin levels are negatively correlated with insulin resistance and free androgens in women with polycystic ovary syndrome

D Panidis, D Rousso, G Koliakos, A Kourtis, I Katsikis… - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: This study was designed to:[1] measure, for the first time, metastin (kisspeptin)
levels in women with polycystic ovary syndrome (PCOS), a condition associated with …

Polycystic ovary syndrome (PCOS) and kisspeptin–A Sri Lankan study

B Umayal, SN Jayakody… - Journal of …, 2019 - journals.lww.com
Aim: We aimed to measure serum kisspeptin levels of subjects with well-characterized
PCOS versus controls and explore any correlation between kisspeptin and PCOS-related …