Polycystic ovary syndrome (PCOS) and kisspeptin–A Sri Lankan study
B Umayal, SN Jayakody… - Journal of …, 2019 - journals.lww.com
Aim: We aimed to measure serum kisspeptin levels of subjects with well-characterized
PCOS versus controls and explore any correlation between kisspeptin and PCOS-related …
PCOS versus controls and explore any correlation between kisspeptin and PCOS-related …
Circulating kisspeptin levels exhibit sexual dimorphism in adults, are increased in obese prepubertal girls and do not suffer modifications in girls with idiopathic central …
J Pita, V Barrios, T Gavela-Pérez, GÁ Martos-Moreno… - Peptides, 2011 - Elsevier
The system KISS1–KISS1R is one of the main regulators of the hypothalamic-pituitary-
gonadal axis and constitutes a link between metabolism and reproduction through its …
gonadal axis and constitutes a link between metabolism and reproduction through its …
Kisspeptin and polycystic ovary syndrome
R Tang, X Ding, J Zhu - Frontiers in endocrinology, 2019 - frontiersin.org
Although the pathogenesis of Polycystic Ovary Syndrome (PCOS) is still unclear, the
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity
The neuropeptide kisspeptin regulates reproduction by stimulating gonadotropin-releasing
hormone (GnRH) neurons via the kisspeptin receptor KISS1R. In addition to GnRH neurons …
hormone (GnRH) neurons via the kisspeptin receptor KISS1R. In addition to GnRH neurons …
KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake
RE Brown, SA Imran, E Ur, M Wilkinson - Molecular and cellular …, 2008 - Elsevier
Hypothalamic KiSS-1 gene expression is critical for the maintenance of reproductive
function, and levels are attenuated by sex hormones and by food restriction, providing a link …
function, and levels are attenuated by sex hormones and by food restriction, providing a link …
There is kisspeptin–and then there is kisspeptin
MA Hussain, WJ Song, A Wolfe - Trends in Endocrinology & Metabolism, 2015 - cell.com
While kisspeptin was initially found to function as a metastasis suppressor, after
identification of its receptor KISS1R and their expression profiles in tissues such as the …
identification of its receptor KISS1R and their expression profiles in tissues such as the …
Kisspeptin and metabolism: the brain and beyond
Apart from the well-established role of kisspeptin (Kp) in the regulation of reproductive
functions, recent data described its action in the control of metabolism. Of particular interest …
functions, recent data described its action in the control of metabolism. Of particular interest …
Is there a role for kisspeptin in pathogenesis of polycystic ovary syndrome?
Aim: To investigate association of kisspeptin levels in infertile women with different ovarian
reserve patterns. Materials and methods: In this prospective cross-sectional study, 157 …
reserve patterns. Materials and methods: In this prospective cross-sectional study, 157 …
Effects of high-fat diet-induced obesity and diabetes on Kiss1 and GPR54 expression in the hypothalamic–pituitary–gonadal (HPG) axis and peripheral organs (fat …
Recent data indicates that kisspeptin, encoded by the KISS1 gene, could play a role in
transducing metabolic information into the hypothalamic–pituitary–gonadal (HPG) axis, the …
transducing metabolic information into the hypothalamic–pituitary–gonadal (HPG) axis, the …
Circulating spexin levels negatively correlate with age, BMI, fasting glucose, and triglycerides in healthy adult women
Context Spexin is a newly identified neuropeptide that is involved in satiety control, glucose,
and lipids metabolism. It has also been related to human diseases, such as obesity and type …
and lipids metabolism. It has also been related to human diseases, such as obesity and type …