The receptor for advanced glycated end products (RAGE) is a multiligand receptor that is
implicated in the pathogenesis of various diseases, including diabetic complications …

Advanced glycation end products (AGEs) accumulate with age and at an accelerated rate in
diabetes. AGEs bind cell-surface receptors including the receptor for advanced glycation …

Background: Type 2 diabetes mellitus (T2DM) is the most common lifestyle disease affecting
all countries. Due to its asymptomatic onset, it is often diagnosed after irreversible vascular …

Albumin, the major circulating protein in blood plasma, can be subjected to an increased
level of glycation in a diabetic context. Albumin exerts crucial pharmacological activities …

The drug binding ability of serum albumin might get affected as a result of its glycation under
diabetic conditions. It requires not only an understanding of the effect of glycation of the …

Early glycation involves attachment of glucose on ε-NH2 of lysine residues. Human serum
albumin (HSA), a lysine rich protein, is highly prone to non-enzymatic glycation. In this study …

Diabetes mellitus, a metabolic disorder that is characterized by elevated blood glucose
levels, is common throughout the world and its prevalence is steadily increasing. Early …

Introduction: Human serum albumin (HSA) is a multifaceted protein with vital physiological
functions. It is the most abundant plasma protein with inherent capability to bind to diverse …

Aim To understand the mechanism of glycation of albumin and effects on cysteinylation and
methionine oxidation. Methods The in vitro glycation of HSA and BSA was studied with …

Receptor for advanced glycation end products (RAGE) is a multiligand receptor that is
engaged in many pathological processes. Potentially beneficial modification of its activity …