Introduction: Secondary hyperparathyroidism (SHPT) is a common complication associated
with morbidity and mortality among hemodialysis (HD) patients. Objectives: The current …

Background Secondary hyperparathyroidism (SHPT) is a common complication of chronic
kidney disease (CKD) patients on dialysis, associated with increased cardiovascular …

The objective of this study was to determine the impact of calcium sensing receptor (CASR)
A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to …

Abstract Nephrolithiasis, secondary hyperparathyroidism (sHPT), and cardiovascular
complications are associated with disturbances in Ca handling and contribute to …

Methods: Frequency of CASR rs7652589 nucleotide variants in HD patients (n= 1162) was
compared to that of healthy controls (n= 918) to exclude uremia-related association. HD …

Results There were modest associations of CASR SNPs with increased baseline serum
parathyroid hormone and bone alkaline phosphatase primarily with the minor allele in the …

The present study was performed to investigate the association of calcium-sensing receptor
(CaSR) genotypes with parathyroid hormone (PTH) secretion in hemodialysis patients …

Abstract Background/Aims: The calcium-sensing receptor gene (CASR) rs1801725 variant is
responsible for a non-conservative amino-acid change (A986S) in the calcium-sensing …

Back ground: CaSR al lows para thyroid and kid ney tu bu lar cells to reg u late PTH se cre
tion and tu bu lar cal cium re ab sorption. In the pres ent re port, we ex am ined the re la tion …

Aims: Calcimimetics are effective in reducing parathyroid hormone (PTH) levels in patients
with secondary hyperparathyroidism, but variability in dose response has been noted. We …