The principle factors underlying gastric cancer (GC) development and outcomes are not well
characterized resulting in a paucity of validated therapeutic targets. To identify potential …

For many patients, diabetes Mellitus and Malignancy are frequently encountered
comorbidities. Diabetes affects approximately 10.5% of the global population, while …

Objective. To compare the expression of G‐protein‐coupled estrogen receptor (GPER) in
the junctional zone and outer myometrium of the proliferative and secretory phases of …

Visceral hypersensitivity (VH) is common in irritable bowel syndrome (IBS), and female
patients are more likely to seek healthcare services for IBS‐related abdominal pain …

Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …

Regulators of G protein signaling (RGS) proteins provide timely termination of G protein‐
coupled receptor (GPCR) responses. Serving as a central control point in GPCR signaling …

Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

The role of oestrogen in oncogenesis has been examined extensively, especially in the
context of breast cancer, and receptor modulators are an integral part of targeted treatment …