In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …

Colorectal cancer (CRC) is a common malignancy in both genders with a high death rate,
accounting for about 56,000 each year in the USA only. In this study we examined the …

Although it was described previously for estrogen (E 2) regulation of intestinal epithelial Cl−
and HCO 3− secretion in sex difference, almost nothing is known about the roles of estrogen …

Estrogens play a critical role in many aspects of physiology, particularly female reproductive
function, but also in pathophysiology, and are associated with protection from numerous …

G protein‐coupled estrogen receptor (GPER) is identified as a critical estrogen receptor, in
addition to the classical estrogen receptors ERα and ERβ. In ERα‐negative ovarian cancer …

Estrogen is a steroid hormone involved in the regulation of a wide array of processes that
include reproduction, sexual development, behavior, stress responses, bone integrity …

Oestrogens and their receptors contribute broadly to physiology and diseases. In
premenopausal women, endogenous oestrogens protect against cardiovascular, metabolic …

Ovarian hormone deficiency decreases and estrogen (E2) and growth hormone (GH)
administrations increase intestinal absorption of calcium (Ca++). However, the underlying …

The eukaryotic nuclear receptors (NRs) super-family of transcriptional factors include the
estrogen-related receptors (ERRs) that have diverse roles in control of cellular energy …

The last few decades have revealed increasing complexity and depth to our knowledge of
receptor-mediated estrogen signaling. Nuclear estrogen receptors (ERs) ERα and ERβ …