Genetic and environmental factors jointly determine the susceptibility to develop Multiple
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …

Viruses are directly or indirectly implicated in multiple sclerosis (MS). Here, we review the
evidence on the virus-related pathophysiology of MS, introduce common experimental …

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological
cause remains elusive. Multiple triggering factors have been suggested, including …

A large body of immunologic, epidemiologic, and genetic data indicate that tissue injury in
multiple sclerosis (MS) results from an abnormal immune response to one or more myelin …

One of the most frequent statements, provided in different variations in the introduction of
experimental studies on multiple sclerosis (MS), is that “Multiple sclerosis is a demyelinating …

Publisher Summary Multiple sclerosis (MS) is the most prevalent demyelinating disease of
young adults, affecting an estimated 300,000 individuals in the United States alone. The …

Polymicrobial infections have been associated with plausible immune mediated diseases,
including multiple sclerosis (MS). Virus infection can prime autoimmune T cells specific for …

Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …

Multiple sclerosis is a chronic immune-mediated disease of the central nervous system that
develops in young adults with a complex genetic predisposition. Similar to other …

MS is an immune mediated disease of the central nervous system (CNS) characterized by
demyelination, axonal damage and neurologic disability. The primary cause of this CNS …