The role of redox dysregulation in the effects of prenatal stress on embryonic interneuron migration

J Bittle, EC Menezes, ML McCormick, DR Spitz… - Cerebral …, 2019 - academic.oup.com
Maternal stress during pregnancy is associated with increased risk of psychiatric disorders
in offspring, but embryonic brain mechanisms disrupted by prenatal stress are not fully …

Prenatal stress induces translational disruption associated with myelination deficits

GK Crombie, HK Palliser, JC Shaw, BA Hanley… - Dev. Neurosci, 2023 - karger.com
Disruptions to neurodevelopment are known to be linked to behavioral disorders in
childhood and into adulthood. The fetal brain is extremely vulnerable to stimuli that alter …

The role of glucocorticoid, interleukin-1β, and antioxidants in prenatal stress effects on embryonic microglia

J Bittle, HE Stevens - Journal of neuroinflammation, 2018 - Springer
Maternal stress during pregnancy is associated with an increased risk of psychopathology in
offspring. Resident immune cells of the brain, microglia, may be mediators of prenatal stress …

Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex

HE Stevens, T Su, Y Yanagawa… - Psychoneuroendocrinology, 2013 - Elsevier
Prenatal stress has been widely demonstrated to have links with behavioral problems in
clinical populations and animal models, however, few investigations have examined the …

Maternal P7C3-A20 treatment protects offspring from neuropsychiatric sequelae of prenatal stress

R Schroeder, P Sridharan, L Nguyen… - Antioxidants & redox …, 2021 - liebertpub.com
Aims: Impaired embryonic cortical interneuron development from prenatal stress is linked to
adult neuropsychiatric impairment, stemming in part from excessive generation of reactive …

The placenta as a mediator of stress effects on neurodevelopmental reprogramming

SL Bronson, TL Bale - Neuropsychopharmacology, 2016 - nature.com
Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …

[HTML][HTML] Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring's brain and behavior

H Scott, TJ Phillips, Y Sze, A Alfieri, MF Rogers… - Neurobiology of …, 2020 - Elsevier
Maternal exposure to stress during pregnancy is associated with an increased risk of
psychiatric disorders in the offspring in later life. The mechanisms through which the effects …

[HTML][HTML] Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells

JE Le Belle, J Sperry, A Ngo, Y Ghochani, DR Laks… - Stem cell reports, 2014 - cell.com
A period of mild brain overgrowth with an unknown etiology has been identified as one of
the most common phenotypes in autism. Here, we test the hypothesis that maternal …

Cellular stress mechanisms of prenatal maternal stress: Heat shock factors and oxidative stress

J Dowell, BA Elser, RE Schroeder, HE Stevens - Neuroscience letters, 2019 - Elsevier
Abstract Development of the brain prenatally is affected by maternal experience and
exposure. Prenatal maternal psychological stress changes brain development and results in …

Maternal stress in pregnancy affects myelination and neurosteroid regulatory pathways in the guinea pig cerebellum

GA Bennett, HK Palliser, JC Shaw, KL Palazzi… - Stress, 2017 - Taylor & Francis
Prenatal stress predisposes offspring to behavioral pathologies. These may be attributed to
effects on cerebellar neurosteroids and GABAergic inhibitory signaling, which can be linked …