Phylogenetic analyses suggest multiple changes of substrate specificity within the glycosyl hydrolase 20 family

J Intra, G Pavesi, DS Horner - BMC Evolutionary Biology, 2008 - Springer
Background Beta-N-acetylhexosaminidases belonging to the glycosyl hydrolase 20 (GH20)
family are involved in the removal of terminal β-glycosidacally linked N-acetylhexosamine …

Bioinformatic, genetic, and biochemical evidence that some glycoside hydrolase family 42 β-galactosidases are arabinogalactan type I oligomer hydrolases

S Shipkowski, JE Brenchley - Applied and Environmental …, 2006 - Am Soc Microbiol
Glycoside hydrolases are organized into glycoside hydrolase families (GHFs) and within this
larger group, the β-galactosidases are members of four families: 1, 2, 35, and 42. Most …

Structural and Biochemical Insights into the Peptidoglycan Hydrolase Domain of FlgJ from Salmonella typhimurium

P Zaloba, BA Bailey-Elkin, M Derksen, BL Mark - PLoS One, 2016 - journals.plos.org
FlgJ is a glycoside hydrolase (GH) enzyme belonging to the Carbohydrate Active enZyme
(CAZy) family GH73. It facilitates passage of the bacterial flagellum through the …

Role of glycoside phosphorylases in mannose foraging by human gut bacteria

S Ladeveze, L Tarquis, DA Cecchini, J Bercovici… - Journal of Biological …, 2013 - ASBMB
To metabolize both dietary fiber constituent carbohydrates and host glycans lining the
intestinal epithelium, gut bacteria produce a wide range of carbohydrate-active enzymes, of …

Structural insights into polysaccharide recognition by Flavobacterium johnsoniae dextranase, a member of glycoside hydrolase family 31

K Tsutsumi, Y Gozu, A Nishikawa… - The FEBS …, 2020 - Wiley Online Library
Glycoside hydrolase family (GH) 31 contains a large variety of enzymes, but the major
members are enzymes that act on relatively small oligosaccharides such as α‐glucosidase …

The identification of the catalytic nucleophiles of two β-galactosidases from glycoside hydrolase family 35

JE Blanchard, L Gal, S He, J Foisy, RAJ Warren… - Carbohydrate …, 2001 - Elsevier
The β-galactosidases from Xanthomonas manihotis (β-Gal Xmn) and Bacillus circulans (β-
Gal-3 Bcir) are retaining glycosidases that hydrolyze glycosidic bonds through a double …

The molecular mechanism of thermostable α-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies

R Merceron, M Foucault, R Haser, R Mattes… - Journal of Biological …, 2012 - ASBMB
The α-galactosidase AgaA from the thermophilic microorganism Geobacillus
stearothermophilus has great industrial potential because it is fully active at 338 K against …

Trimeric crystal structure of the glycoside hydrolase family 42 β-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose

M Hidaka, S Fushinobu, N Ohtsu, H Motoshima… - Journal of molecular …, 2002 - Elsevier
The β-galactosidase from an extreme thermophile, Thermus thermophilus A4 (A4-β-Gal), is
thermostable and belongs to the glycoside hydrolase family 42 (GH-42). As the first known …

Aromatic residue on β→ α loop 1 in the catalytic domain is important to the transglycosylation specificity of glycoside hydrolase family 31 α-glucosidase

KM Song, M Okuyama, M Nishimura… - Bioscience …, 2013 - Taylor & Francis
The specificity for the α-1, 4-and α-1, 6-glucosidic linkages varies among glycoside
hydrolase family 31 α-glucosidases. This difference in substrate specificity has been …

Structural elements determining the transglycosylating activity of glycoside hydrolase family 57 glycogen branching enzymes

G Xiang, H Leemhuis… - … : structure, function, and …, 2022 - Wiley Online Library
Glycoside hydrolase family 57 glycogen branching enzymes (GH57GBE) catalyze the
formation of an α‐1, 6 glycosidic bond between α‐1, 4 linked glucooliogosaccharides. As an …