Background Exposure to traffic-generated emissions is associated with the development
and exacerbation of inflammatory lung disorders such as chronic obstructive pulmonary …

Pulmonary responses to diesel exhaust particles (DEP) exposure are mediated through
enhanced production of reactive oxygen species (ROS) and nitric oxide (NO) by alveolar …

Although several studies have reported that diesel exhaust particles (DEP) affect
cardiorespiratory health in animals and humans, the effect of DEP on animal models with …

Background The gut microbiota plays a vital role in host homeostasis and is associated with
inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is …

Exposure to traffic-related ambient air pollution, such as diesel exhaust particles (DEP), is
associated with adverse health outcomes, especially in individuals with preexisting …

Diesel exhaust particles (DEPs) have been shown to activate oxidant generation by alveolar
macrophages (AMs), alter xenobiotic metabolic pathways, and modify the balance of pro …

Background Epidemiologic studies associate childhood exposure to traffic-related air
pollution with increased respiratory infections and asthmatic and allergic symptoms. The …

Background Inhalation of diesel exhaust impairs vascular function in man, by a mechanism
that has yet to be fully established. We hypothesised that pulmonary exposure to diesel …

The effect of diesel exhaust particulate (DEP) exposure on innate, cellular and humoral
pulmonary immunity was studied using high-dose, acute-exposure rat, mouse, and cell …

Air pollution has been documented to contribute to severe respiratory diseases like asthma
and chronic obstructive pulmonary disorder (COPD). Although these diseases demonstrate …