Aspirin versus clopidogrel monotherapy for the treatment of patients with stable coronary artery disease: a systematic review and meta-analysis

J Yuan, GM Xu, J Ding - Advances in therapy, 2019 - Springer
Introduction Although aspirin (ASA) is the mainstay of treatment for the prevention of
recurrent ischemic stroke, the Clopidogrel versus Aspirin in Patients at Risk of Ischemic …

The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of …

SR Mehta, S Yusuf - European heart journal, 2000 - europepmc.org
Background Other than aspirin, there are few oral antithrombotic treatments with proven
efficacy in patients with acute coronary syndrome. In this report, we present the rationale …

Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable …

RJG Peters, SR Mehta, KAA Fox, F Zhao, BS Lewis… - Circulation, 2003 - Am Heart Assoc
Background—We studied the benefits and risks of adding clopidogrel to different doses of
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and …

Clopidogrel use as single antiplatelet therapy in outpatients with stable coronary artery disease: prevalence, correlates and association with prognosis (from the …

G Lemesle, G Schurtz, T Meurice, O Tricot, N Lemaire… - Cardiology, 2016 - karger.com
Background: Clopidogrel use as single antiplatelet therapy (SAPT) has never been
evaluated in stable coronary artery disease (CAD) outpatients either as compared to …

Clopidogrel monotherapy versus aspirin monotherapy in patients with established cardiovascular disease: systematic review and meta-analysis

PT Tasoudis, IG Kyriakoulis, D Sagris… - Thrombosis and …, 2022 - thieme-connect.com
Background There is no clear consensus on whether aspirin offers better outcomes in terms
of secondary cardiovascular disease prevention compared with clopidogrel. Objective The …

Aspirin and clopidogrel: a sweeping combination in cardiology

AS Manolis, S Tzeis, G Andrikopoulos… - Current Medicinal …, 2005 - ingentaconnect.com
Platelets play a pivotal role in the pathogenesis of atherothrombosis, believed to be
integrally involved in both the development and progression of atherosclerotic heart …

Long-term combination therapy with aspirin and clopidogrel

CR Kumana, G Cheung, IJ Lauder… - Journal of …, 2004 - journals.sagepub.com
The possible additive antiplatelet effects of aspirin and clopidogrel have been explored in
the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) and Management …

Benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic events

PA Ringleb, DL Bhatt, AT Hirsch, EJ Topol, W Hacke - Stroke, 2004 - Am Heart Assoc
Background and Purpose—The goal of this study was to examine the influence of
preexisting symptomatic atherosclerotic disease on subsequent ischemic event rates and …

Benefit of clopidogrel in patients with acute coronary syndromes without ST-segment elevation in various risk groups

A Budaj, S Yusuf, SR Mehta, KAA Fox, G Tognoni… - Circulation, 2002 - Am Heart Assoc
Background—The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial
demonstrated that clopidogrel, given early and continued long term, was superior to placebo …

Medical management of stable coronary artery disease

M Pflieger, BT Winslow, K Mills, IM Dauber - American family physician, 2011 - aafp.org
All patients with stable coronary artery disease require medical therapy to prevent disease
progression and recurrent cardiovascular events. Three classes of medication are essential …