Background: Although clopidogrel plus aspirin is more effective than aspirin alone in
preventing subsequent vascular events in patients with unstable angina, the cost …

Ischemic heart disease (IHD) represents a pathophysiologic continuum consisting of stable
angina, unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment …

Background: The CAPRIE study showed the superiority of clopidogrel over acetylsalicylic
acid (ASA) for reducing the combined risk of major atherothrombotic events in patients with …

Antiplatelet drugs have been shown to prevent a range of atherothrombotic events, including
transient ischaemic attack (TIA) and ischaemic stroke. Clopidogrel and ticlopidine are …

Background: A systematic review and network meta-analysis (NMA) were conducted to
explore the efficacy and safety of different antiplatelet or anticoagulation drugs in chronic …

Despite many recent advancements in the treatment of coronary heart disease, it continues
to be an important source of patient morbidity and mortality as well as a significant source of …

Antiplatelet agents are central to the treatment and prevention of cardiovascular disease.
Although aspirin is the most widely used agent, randomized trials have assessed whether …

Aims To evaluate clinical outcomes associated with the combined use of clopidogrel and
statins vs. clopidogrel alone on a background of aspirin therapy in patients with the spectrum …

BACKGROUND: The CURE study demonstrated the benefit of clopidogrel in patients with
non–ST elevation (NSTE) acute coronary syndromes (ACSs), including those undergoing …

Most guidelines recommend indefinite use of aspirin in patients at increased
atherothrombotic risk. Dual antiplatelet therapy (aspirin/clopidogrel) is significantly more …